Evidence map›Paper›PMID 28832493›Full record

ArticleNutrients2017

Modulation of Gut Microbiota of Overweight Mice by Agavins and Their Association with Body Weight Loss.

Alicia Huazano-García, Hakdong Shin, Mercedes G López

Registry-linked trialAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04555447 (Gastrointestinal Tolerability to Increasing Doses of Agavins and Impact on Gut Microbiota, Fecal Metabolites, and Metabolic Biomarkers in Healthy and Obese Subjects), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04555447 nacompletednot on this mapstarted 2019, after this paper: background citation

Gastrointestinal Tolerability to Increasing Doses of Agavins and Impact on Gut Microbiota, Fecal Metabolites, and Metabolic Biomarkers in Healthy and Obese Subjects

TypeinterventionalSponsorCentro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional-Unidad IrapuatoRan2019 to 2019Enrolled52ConditionsObesity, HealthyArmsAgavins (prebiotic fiber), Placebo
3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Agave Fructans in Oaxaca's Emblematic Specimens:Plants (Basel, Switzerland) · 2022
    Article
  4. Agave Syrup: Chemical Analysis and Nutritional Profile, Applications in the Food Industry and Health Impacts.International journal of environmental research and public health · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Lung and Gut Microbiota Changes Associated withInternational journal of molecular sciences · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in immunology · 2021
    Article
  16. Article
  17. Article
  18. Evolution of Fructans inFrontiers in nutrition · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alicia Huazano-GarcíaDepartamento de Biotecnología y Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN, Unidad Irapuato 36821, México. ahuazano@ira.cinvestav.mx.
Hakdong ShinFaculty of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul 05006, Korea. hakdong.shin@gmail.com.
Mercedes G LópezDepartamento de Biotecnología y Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN, Unidad Irapuato 36821, México. mlopez@ira.cinvestav.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agavins consumption has led to accelerated body weight loss in mice. We investigated the changes on cecal microbiota and short-chain fatty acids (SCFA) associated with body weight loss in overweight mice. Firstly, mice were fed with standard (ST5) or high-fat (HF5) diet for five weeks. Secondly, overweight mice were shifted to standard diet alone (HF-ST10) or supplemented with agavins (HF-ST + A10) or oligofructose (HF-ST + O10), for five more weeks. Cecal contents were collected before and after supplementation to determine microbiota and SCFA concentrations. At the end of first phase, HF5 mice showed a significant increase of body weight, which was associated with reduction of cecal microbiota diversity (PD whole tree; non-parametric

Indexed as

PrebioticsAnimalsAnti-Obesity AgentsBacteriaCecumDiet, High-FatDisease Models, AnimalFatty AcidsFructansGastrointestinal MicrobiomeMaleMice, Inbred C57BLOligosaccharidesOverweightWeight LossAnti-Obesity AgentsFatty AcidsFructansoligofructoseOligosaccharidesPrebioticsagavinsbody weight lossmicrobiotaoverweightprebioticsshort chain fatty acids

Identifiers

PMID28832493
PMCPMC5622678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.