Evidence map›Paper›PMID 28831864›Full record

ArticleJournal of aging and health2019

Aging, Health, and Quality of Life for Older People Living With HIV in Sub-Saharan Africa: A Review and Proposed Conceptual Framework.

Mark J Siedner

Abstract read
In one paragraph

Article in Journal of aging and health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 2 countries.

Mark J Siedner1 Harvard Medical School, Boston, MA, USA.
Massachusetts General Hospital · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Alan David Levine · 1994 to 2026
$50.0M
Developing Research At The Interface Of HIV And AgingR24AG044325 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HIGH, KEVIN P. · 2013 to 2017
$2.4M
Behavioral Aspects of Low-cost Medical Devices to Improve HIV CareK23MH099916 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SIEDNER, MARK J · 2013 to 2017
$917k
Epidemiology of atherosclerosis among older-age individuals with HIV in UgandaR21HL124712 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SIEDNER, MARK J · 2014 to 2015
$332k
NHLBI NIH HHS R21 HL124712NIAID NIH HHS P30 AI036219NIAID NIH HHS P30 AI060354NIA NIH HHS R24 AG044325NIMH NIH HHS K23 MH099916
6 · The paper itself

Abstract

objectiveThe number of people living with HIV (PLWH) over 50 years old in sub-Saharan Africa is predicted to triple in the coming decades, to 6-10 million. Yet, there is a paucity of data on the determinants of health and quality of life for older PLWH in the region.

methodsA review was undertaken to describe the impact of HIV infection on aging for PLWH in sub-Saharan Africa.

resultsWe (a) summarize the pathophysiology and epidemiology of aging with HIV in resource-rich settings, and (b) describe how these relationships might differ in sub-Saharan Africa, (c) propose a conceptual framework to describe determinants of quality of life for older PLWH, and (d) suggest priority research areas needed to ensure long-term gains in quality of life for PLWH in the region.

conclusionsDifferences in traditional, lifestyle, and envirnomental risk factors, as well as unique features of HIV epidemiology and care delivery appear to substantially alter the contribution of HIV to aging in sub-Saharan Africa. Meanwhile, unique preferences and conceptualizations of quality of life will require novel measurement and intervention tools. An expanded research and public health infrastructure is needed to ensure that gains made in HIV prevention and treamtent are translated into long-term benefits in this region.

Indexed as

AgingHealth Status DisparitiesQuality of LifeAfrica South of the SaharaAgedDelivery of Health CareEpidemiologic FactorsFemaleGeriatric AssessmentHealth Services Needs and DemandHIV InfectionsHumansMaleMiddle AgedRisk FactorsaginggerontologyHIV/AIDSinflammationnoncommunicable diseasessub-Saharan Africa

Identifiers

PMID28831864
PMCPMC6019109
OpenAlexW2747544878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.