ArticleJournal of biomedical optics2017
Feasibility of spatial frequency-domain imaging for monitoring palpable breast lesions.
Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Structured light imaging mesoscopy: detection of embedded morphological changes in superficial tissues.Journal of biomedical optics · 2025Article
- Monte Carlo simulation of spatial frequency domain imaging for breast tumors during compression.Journal of biomedical optics · 2024Article
- Cross-wavelength calibrating method for real-time imaging of tissue optical properties using frequency-domain diffuse optical spectroscopy.Biomedical optics express · 2024Article
- Analysis of Light Penetration Depth in Apple Tissues by Depth-Resolved Spatial-Frequency Domain Imaging.Foods (Basel, Switzerland) · 2023Article
- Spatial frequency domain imaging for monitoring immune-mediated chemotherapy treatment response and resistance in a murine breast cancer model.Scientific reports · 2022Article
- Two-layer analytical model for estimation of layer thickness and flow using Diffuse Correlation Spectroscopy.PloS one · 2022Article
- High optode-density wearable diffuse optical probe for monitoring paced breathing hemodynamics in breast tissue.Journal of biomedical optics · 2021Article
- Dual-DMD hyperspectral spatial frequency domain imaging (SFDI) using dispersed broadband illumination with a demonstration of blood stain spectral monitoring.Biomedical optics express · 2021Article
- Optical sampling depth in the spatial frequency domain.Journal of biomedical optics · 2019Article
- Microvascular imaging of the skin.Physics in medicine and biology · 2019Review
- Optical property uncertainty estimates for spatial frequency domain imaging.Biomedical optics express · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In breast cancer diagnosis and therapy monitoring, there is a need for frequent, noninvasive disease progression evaluation. Breast tumors differ from healthy tissue in mechanical stiffness as well as optical properties, which allows optical methods to detect and monitor breast lesions noninvasively. Spatial frequency-domain imaging (SFDI) is a reflectance-based diffuse optical method that can yield two-dimensional images of absolute optical properties of tissue with an inexpensive and portable system, although depth penetration is limited. Since the absorption coefficient of breast tissue is relatively low and the tissue is quite flexible, there is an opportunity for compression of tissue to bring stiff, palpable breast lesions within the detection range of SFDI. Sixteen breast tissue-mimicking phantoms were fabricated containing stiffer, more highly absorbing tumor-mimicking inclusions of varying absorption contrast and depth. These phantoms were imaged with an SFDI system at five levels of compression. An increase in absorption contrast was observed with compression, and reliable detection of each inclusion was achieved when compression was sufficient to bring the inclusion center within ∼12 mm of the phantom surface. At highest compression level, contrasts achieved with this system were comparable to those measured with single source-detector near-infrared spectroscopy.
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