Evidence map›Paper›PMID 28831755›Full record

ArticleEnvironmental science and pollution research international2017

A model of natural degradation of 17-α-ethinylestradiol in surface water and identification of degradation products by GC-MS.

Tomas Nejedly, Jiri Klimes

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tomas NejedlyFaculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Charles University in Prague, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic. nejet6aa@faf.cuni.cz.
Jiri KlimesFaculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Charles University in Prague, Heyrovského 1203, 500 05, Hradec Králové, Czech Republic.
Charles University · CZ

Funding

Univerzita Karlova v Praze SVV 260 183
6 · The paper itself

Abstract

Over the past decade, the environment has been polluted by a wide spectrum of exogenous chemicals and environmental analysis has become one of the most progressive parts of analytical research. The aim of this work was to determine the kinetics of natural degradation, and to identify the degradation products of the massively used estrogenic drug, 17-α-ethinylestradiol. The photodegradation, oxidation and thermostability conditions were selected according to ICH requirements for pharmaceutical stability testing. A simple 72-h photodegradation study in purified water exhibited significant first-order kinetics with the kinetic constant k = 0.0303 h

Indexed as

LightEthinyl EstradiolFresh WaterGas Chromatography-Mass SpectrometryKineticsModels, TheoreticalPhotolysisSeawaterWater Pollutants, ChemicalEthinyl EstradiolWater Pollutants, Chemical17-Alpha-ethinylestradiolDegradation kineticEndocrine disruptorEnvironmental modelNatural degradation

Identifiers

PMID28831755
OpenAlexW2749966183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.