ArticleChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2017
Recurrent establishment of de novo centromeres in the pericentromeric region of maize chromosome 3.
Article in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Post-polyploidization centromere evolution in cotton.Nature genetics · 2025Article
- Stable minichromosome and functional neocentromere derived from rye 7R chromosome arm.BMC plant biology · 2024Article
- Translocations and inversions: major chromosomal rearrangements during Vigna (Leguminosae) evolution.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Pan-centromere reveals widespread centromere repositioning of soybean genomes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Centromere repositioning and shifts in wheat evolution.Plant communications · 2023Article
- BAC- and oligo-FISH mapping reveals chromosome evolution among Vigna angularis, V. unguiculata, and Phaseolus vulgaris.Chromosoma · 2021Article
- Charting the genomic landscape of seed-free plants.Nature plants · 2021Review
- The Genomics of Plant Satellite DNA.Progress in molecular and subcellular biology · 2021Review
- Rapid Birth or Death of Centromeres on Fragmented Chromosomes in Maize.The Plant cell · 2020Article
- Genome Evolution in Arabideae Was Marked by Frequent Centromere Repositioning.The Plant cell · 2020Article
- Fluorescence in situ hybridization in plants: recent developments and future applications.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2019Review
- Extraordinary centromeres: differences in the meiotic chromosomes of two rock lizards speciesPeerJ · 2019Article
- What is behind "centromere repositioning"?Chromosoma · 2018Review
- Barbara McClintock's Unsolved Chromosomal Mysteries: Parallels to Common Rearrangements and Karyotype Evolution.The Plant cell · 2018Article
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Authors and funding
6 authors.
Funding
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Abstract
Centromeres can arise de novo from non-centromeric regions, which are often called "neocentromeres." Neocentromere formation provides the best evidence for the concept that centromere function is not determined by the underlying DNA sequences, but controlled by poorly understood epigenetic mechanisms. Numerous neocentromeres have been reported in several plant and animal species. However, it has been elusive how and why a specific chromosomal region is chosen to be a new centromere during the neocentromere activation events. We report recurrent establishment of neocentromeres in a pericentromeric region of chromosome 3 in maize (Zea mays). This latent region is located in the short arm and is only 2 Mb away from the centromere (Cen3) of chromosome 3. At least three independent neocentromere activation events, which were likely induced by different mechanisms, occurred within this latent region. We mapped the binding domains of CENH3, the centromere-specific H3 histone variant, of the three neocentromeres and analyzed the genomic and epigenomic features associated with Cen3, the de novo centromeres and an inactivated centromere derived from an ancestral chromosome. Our results indicate that lack of genes and transcription and a relatively high level of DNA methylation in this pericentromeric region may provide a favorable chromatin environment for neocentromere activation.
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