Evidence map›Paper›PMID 28831738›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2017

Epidemiology from Tweets: Estimating Misuse of Prescription Opioids in the USA from Social Media.

Michael Chary, Nicholas Genes, Christophe Giraud-Carrier, Carl Hanson, Lewis S Nelson, Alex F Manini

Abstract read
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Curation and Extraction of Drug-Related Entities from Reddit Platform.Proceedings. IEEE International Conference on Healthcare Informatics · 2026
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  7. Large-Scale Analysis of Online Questions Related to Opioid Use Disorder on Reddit.Proceedings of the ... International AAAI Conference on Weblogs and Social Media. International AAAI Conference on Weblogs and Social Media · 2025
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  16. Can accurate demographic information about people who use prescription medications nonmedically be derived from Twitter?Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael CharyDepartment of Emergency Medicine, NewYork-Presbyterian/Queens, Queens, NY, USA. mic9180@nyp.org.ORCID 0000-0002-9000-1765
Nicholas GenesDepartment of Emergency Medicine, Mount Sinai Hospital, New York, NY, USA.
Christophe Giraud-CarrierDepartment of Computer Science, Brigham Young University, Provo, UT, USA.
Carl HansonDepartment of Health Science, Brigham Young University, Provo, UT, USA.
Lewis S NelsonDepartment of Emergency Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.
Alex F ManiniDivision of Medical Toxicology, The Icahn School of Medicine, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe misuse of prescription opioids (MUPO) is a leading public health concern. Social media are playing an expanded role in public health research, but there are few methods for estimating established epidemiological metrics from social media. The purpose of this study was to demonstrate that the geographic variation of social media posts mentioning prescription opioid misuse strongly correlates with government estimates of MUPO in the last month.

methodsWe wrote software to acquire publicly available tweets from Twitter from 2012 to 2014 that contained at least one keyword related to prescription opioid use (n = 3,611,528). A medical toxicologist and emergency physician curated the list of keywords. We used the semantic distance (SemD) to automatically quantify the similarity of meaning between tweets and identify tweets that mentioned MUPO. We defined the SemD between two words as the shortest distance between the two corresponding word-centroids. Each word-centroid represented all recognized meanings of a word. We validated this automatic identification with manual curation. We used Twitter metadata to estimate the location of each tweet. We compared our estimated geographic distribution with the 2013-2015 National Surveys on Drug Usage and Health (NSDUH).

resultsTweets that mentioned MUPO formed a distinct cluster far away from semantically unrelated tweets. The state-by-state correlation between Twitter and NSDUH was highly significant across all NSDUH survey years. The correlation was strongest between Twitter and NSDUH data from those aged 18-25 (r = 0.94, p < 0.01 for 2012; r = 0.94, p < 0.01 for 2013; r = 0.71, p = 0.02 for 2014). The correlation was driven by discussions of opioid use, even after controlling for geographic variation in Twitter usage.

conclusionsMentions of MUPO on Twitter correlate strongly with state-by-state NSDUH estimates of MUPO. We have also demonstrated that a natural language processing can be used to analyze social media to provide insights for syndromic toxicosurveillance.

Indexed as

Data MiningHealth SurveysHumansNatural Language ProcessingOpioid-Related DisordersPrescription Drug MisusePrevalencePrincipal Component AnalysisSemanticsSocial MediaSoftware DesignSubstance-Related DisordersTime FactorsUnited StatesComputational linguisticsEpidemiologyMisuseNatural language processingOpioidsSocial media

Identifiers

PMID28831738
PMCPMC5711756

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.