Evidence map›Paper›PMID 28831576›Full record

ReviewInternational orthopaedics2017

Prevention of fracture-related infection: a multidisciplinary care package.

Willem-Jan Metsemakers, Jolien Onsea, Emilie Neutjens, Ester Steffens, Annette Schuermans, Martin McNally, Stefaan Nijs

Abstract readReview
PubMed Publisher
In one paragraph

Review in International orthopaedics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Implementation methods of infection prevention measures in orthopedics and traumatology - a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021
    Pooled it
  2. Pooled it
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  6. Review
  7. Wound infection caused byFrontiers in cellular and infection microbiology · 2026
    Article
  8. Review
  9. Identifying risk factors for systemic complications following fracture-related infection.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
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  11. Review
  12. Article
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  15. Review
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  19. Article
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Willem-Jan MetsemakersDepartment of Trauma Surgery, University Hospital Leuven, Leuven, Belgium. willem-jan.metsemakers@uzleuven.be.ORCID 0000-0002-4114-9093
Jolien OnseaDepartment of Trauma Surgery, University Hospital Leuven, Leuven, Belgium.
Emilie NeutjensDepartment of Biomedical Sciences, Catholic University Leuven, Leuven, Belgium.
Ester SteffensDepartment of Infection Control and Epidemiology, University Hospitals Leuven, Leuven, Belgium.
Annette SchuermansDepartment of Infection Control and Epidemiology, University Hospitals Leuven, Leuven, Belgium.
Martin McNallyThe Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK.
Stefaan NijsDepartment of Trauma Surgery, University Hospital Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fracture-related infection (FRI) remains a challenging complication. It may result in permanent functional loss or even amputation in otherwise healthy patients. For these reasons, it is important to focus attention on prevention. In treatment algorithms for FRI, antibiotic stewardship programmes have already proved their use by means of a multidisciplinary collaboration between microbiologists, surgeons, pharmacists, infectious disease physicians and nursing staff. A similar approach, however, has not been described for infection prevention. As a first step towards achieving a multidisciplinary care package for infection prevention, this review summarises the most recent guidelines published by the World Health Organization (WHO) and US National Institutes of Health Centers for Disease Control and Prevention (CDC), primarily focusing on the musculoskeletal trauma patient. The implementation of these guidelines, together with close collaboration between infection control physicians, surgeons, anaesthesiologists and nursing staff, can potentially have a beneficial effect on the rate of FRI after musculoskeletal trauma surgery. It must be stated that most evidence presented here in support of these guidelines was not obtained from musculoskeletal trauma research. Although most preventive measures described in these studies can be generalised to the musculoskeletal trauma patient, there are still important differences with nontrauma patients that require further attention. Future research should therefore focus more on this very defined patient population and more specifically on FRI prevention.

Indexed as

Fracture Fixation, InternalFractures, BoneHumansInfection ControlInterdisciplinary CommunicationPractice Guidelines as TopicSurgical Wound InfectionUnited StatesFracture-related infectionInfection preventionMultidisciplinary care packageMusculoskeletal trauma surgeryPrevention

Identifiers

PMID28831576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.