Evidence map›Paper›PMID 28831485›Full record

ArticleThe Analyst2017

An ultrasensitive enzyme-free electrochemical immunosensor based on redox cycling amplification using methylene blue.

Gorachand Dutta, Peter B Lillehoj

Abstract read
In one paragraph

Article in The Analyst, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  11. Urine and Saliva: Relevant Specimens for Malaria Diagnosis?Diagnostics (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gorachand DuttaDepartment of Mechanical Engineering, Michigan State University, East Lansing, MI 48824, USA. lillehoj@egr.msu.edu.
Peter B Lillehoj
Michigan State University · US

Funding

Rapid in-field malaria diagnosis, prognosis and monitoring using a mobile phoneR01AI113257 · NIAID · RICE UNIVERSITY · PI LILLEHOJ, PETER B · 2015 to 2018
$1.8M
NIAID NIH HHS R01 AI113257
6 · The paper itself

Abstract

We report a new enzyme-free electrochemical sensor for ultrasensitive measurements of protein biomarkers in plasma and whole blood samples based on a unique electrochemical-chemical-chemical (ECC) redox cycling signal amplification scheme. This scheme uses methylene blue (MB) as a redox indicator which undergoes an endergonic reaction with Ru(NH

Indexed as

Biosensing TechniquesElectrochemical TechniquesImmunoassayAntigens, ProtozoanBiomarkersHumansLimit of DetectionMethylene BlueOxidation-ReductionProtozoan ProteinsReproducibility of ResultsAntigens, ProtozoanBiomarkersHRP-2 antigen, Plasmodium falciparumMethylene BlueProtozoan Proteins

Identifiers

PMID28831485
PMCPMC5600201
OpenAlexW2742217896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.