Evidence map›Paper›PMID 28831446›Full record

ArticleJournal of global oncology2017

Identifying and Prioritizing Gaps in Neuroendocrine Tumor Research: A Modified Delphi Process With Patients and Health Care Providers to Set the Research Action Plan for the Newly Formed Commonwealth Neuroendocrine Tumor Collaboration.

Eva Segelov, David Chan, Ben Lawrence, Nick Pavlakis, Hagen F Kennecke, Christopher Jackson, Calvin Law, Simron Singh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of global oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. EMT Molecular Signatures of Pancreatic Neuroendocrine Neoplasms.International journal of molecular sciences · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eva Segelov, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
David Chan, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
Ben Lawrence, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
Nick Pavlakis, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
Hagen F Kennecke, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
Christopher Jackson, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
Calvin Law, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
Simron Singh, University of New South Wales; and , Royal North Shore Hospital, Sydney, Australia; , University of Auckland, Auckland; , University of Otago, Dunedin, New Zealand; , University of British Columbia, Vancouver; and and , Odette Cancer Centre, Toronto, Canada.
North Shore Hospital · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNeuroendocrine tumors (NETs) are a diverse group of malignancies that pose challenges common to all rare tumors. The Commonwealth Neuroendocrine Tumor Collaboration (CommNETS) was established in 2015 to enhance outcomes for patients with NETs in Canada, Australia, and New Zealand. A modified Delphi process was undertaken involving patients, clinicians, and researchers to identify gaps in NETs research to produce a comprehensive and defensible research action plan.

methodsA three-round modified Delphi process was undertaken with larger representation than usual for medical consensus processes. Patient/advocate and health care provider/researcher expert panels undertook Round 1, which canvassed 17 research priorities and 42 potential topics; in Round 2, these priorities were ranked. Round 3 comprised a face-to-face meeting to generate final consensus rankings and formulate the research action plan.

resultsThe Delphi groups consisted of 203 participants in Round 1 (64% health care providers/researchers, 36% patient/advocates; 52% Canadian, 32% Australian, and 17% New Zealander), of whom 132 participated in Round 2. The top eight priorities were biomarker development; peptide receptor radionuclide therapy optimization; trials of new agents in advanced NETs; functional imaging; sequencing therapies for metastatic NETs, including development of validated surrogate end points for studies; pathologic classification; early diagnosis; interventional therapeutics; and curative surgery. Two major areas were ranked significantly higher by patients/advocates: early diagnosis and curative surgery. Six CommNETS working parties were established.

conclusionThis modified Delphi process resulted in a well-founded set of research priorities for the newly formed CommNETS collaboration by involving a large, diverse group of stakeholders. This approach to setting a research agenda for a new collaborative group should be adopted to ensure that research plans reflect unmet needs and priorities in the field.

Identifiers

PMID28831446
PMCPMC5560462
OpenAlexW2530928045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.