SynthesisBioMed research international2017
Pathoanatomic Risk Factors for Instability and Adjacent Segment Disease in Lumbar Spine: How to Use Topping Off?
Synthesis in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- [Adjacent Segment Disease in Lumbar Spine and Lumbosacral Junction Stabilisation: Systematic Review].Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca · 2026Pooled it
- Dynamic Stabilization Adjacent to Fusion versus Posterior Lumbar Interbody Fusion for the Treatment of Lumbar Degenerative Disease: A Meta-Analysis.BioMed research international · 2020Pooled it
- Topping-Off Technology versus Posterior Lumbar Interbody Fusion in the Treatment of Lumbar Disc Herniation: A Meta-Analysis.BioMed research international · 2020Pooled it
- Pooled it
- Patients' knowledge, attitude, and practice toward degenerative lumbar spine disease: A cross-sectional study in Shanxi, China.Scientific reports · 2025Article
- Biomechanical investigation of topping-off technique using an interspinous process device following lumbar interbody fusion under vibration loading.Medical & biological engineering & computing · 2021Article
- Classification and Automated Interpretation of Spinal Posture Data Using a Pathology-Independent Classifier and Explainable Artificial Intelligence (XAI).Sensors (Basel, Switzerland) · 2021Article
- Upper and lower adjacent segment range of motion after fixation of different lumbar spine segments in the goat: anThe Journal of international medical research · 2021Article
- [Postoperative management of weight bearing and rehabilitation after lumbar spinal surgery].Der Orthopade · 2020Review
- [Mid-term effectiveness of Coflex interspinous dynamic internal fixation combined with spinal fusion for lumbar disc degeneration].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe goal of this review is to identify criteria indicating implantation of hybrid system into lumbar spine and to evaluate general benefits of use.
methodsA systematic review of literature was performed using current randomized clinical trials, reviews, and meta-analyses. Data sources included relevant literature of human studies identified through searches of Medline Library until May 2015.
resultsPredisposing factors for Adjacent Segment Disease (ASDi) are discussed in literature: laminar horizontalization, insufficiency of fascia thoracolumbalis, facet tropism, and facet sagittalization. Currently there is no evidence for topping off. There are only 12 studies and these have no consistent statements about use of a hybrid system for avoidance of ASDi.
conclusionHybrid instrumentation of lumbar spine, either with pedicle-based technique or additional spacer, might possibly prevent ASDi from developing in previously damaged segment adjacent to a fusion. Good clinical data proving effectiveness of this new implant technique is as yet unavailable. Thus, currently one must speak of an unevaluated procedure. Various radiological classifications can assist in making a reliable decision as to whether hybrid instrumentation is an appropriate choice of therapy. Pathoanatomical conditions of facet joints and laminae as well as preservation of sagittal balance must also be considered.
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