ArticleProcedia computer science2017
Numerical simulation of a compound capsule in a constricted microchannel.
Article in Procedia computer science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport.Cellular and molecular bioengineering · 2023Article
- Enhancing Adaptive Physics Refinement Simulations Through the Addition of Realistic Red Blood Cell Counts.International Conference for High Performance Computing, Networking, Storage and Analysis : [proceedings]. SC (Conference : Supercomputing) · 2023Article
- Distributed Acceleration of Adhesive Dynamics Simulations.Proceedings of 2022 29th European MPI Users' Group Meeting (EuroMPI/USA'2022) : September 26-28, 2022, Chattanooga, TN. European MPI Users' Group Meeting (29th : 2022 : Chattanooga, Tenn.) · 2022Article
- High Performance Adaptive Physics Refinement to Enable Large-Scale Tracking of Cancer Cell Trajectory.Proceedings. IEEE International Conference on Cluster Computing · 2022Article
- The role of adhesive receptor patterns on cell transport in complex microvessels.Biomechanics and modeling in mechanobiology · 2022Article
- Numerical simulation of intracellular drug delivery via rapid squeezing.Biomicrofluidics · 2021Article
- Investigating the Interaction Between Circulating Tumor Cells and Local HydrodynamicsCellular and molecular bioengineering · 2020Article
- Multi-GPU Immersed Boundary Method Hemodynamics Simulations.Journal of computational science · 2020Article
- Localization of Rolling and Firm-Adhesive Interactions Between Circulating Tumor Cells and the Microvasculature Wall.Cellular and molecular bioengineering · 2020Article
- Suitability of lattice Boltzmann inlet and outlet boundary conditions for simulating flow in image-derived vasculature.International journal for numerical methods in biomedical engineering · 2019Article
- Role of deformable cancer cells on wall shear stress-associated-VEGF secretion by endothelium in microvasculature.PloS one · 2019Article
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Authors and funding
3 authors.
Funding
Abstract
Simulations of the passage of eukaryotic cells through a constricted channel aid in studying the properties of cancer cells and their transport in the bloodstream. Compound capsules, which explicitly model the outer cell membrane and nuclear lamina, have the potential to improve computational model fidelity. However, general simulations of compound capsules transiting a constricted microchannel have not been conducted and the influence of the compound capsule model on computational performance is not well known. In this study, we extend a parallel hemodynamics application to simulate the fluid-structure interaction between compound capsules and fluid. With this framework, we compare the deformation of simple and compound capsules in constricted microchannels, and explore how deformation depends on the capillary number and on the volume fraction of the inner membrane. The computational framework's parallel performance in this setting is evaluated and future development lessons are discussed.
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