Evidence map›Paper›PMID 28831274›Full record

ArticleInternational journal of women's health2017

Biomechanical paradigm and interpretation of female pelvic floor conditions before a treatment.

Vincent Lucente, Heather van Raalte, Miles Murphy, Vladimir Egorov

Registry-linked trialAbstract read
In one paragraph

Article in International journal of women's health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04247555 (Cervix Monitor for Elasticity and Length Measurements), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04247555 unknown statusnot on this mapstarted 2020, after this paper: background citation

Cervix Monitor for Elasticity and Length Measurements

TypeobservationalSponsorAdvanced Tactile Imaging, Inc.Ran2020 to 2022Enrolled270ConditionsPreterm Birth
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Observational
  3. Vaginal tactile imaging: A review.Pelviperineology · 2023
    Article
  4. Biomechanical integrity score of the female pelvic floor.International urogynecology journal · 2022
    Observational
  5. Article
  6. Predictive Value of Biomechanical Mapping for Pelvic Organ Prolapse Surgery.Female pelvic medicine & reconstructive surgery · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vincent LucenteThe Institute for Female Pelvic Medicine and Reconstructive Surgery, Allentown, PA, USA.
Heather van RaaltePrinceton Urogynecology, Princeton, NJ, USA.
Miles MurphyThe Institute for Female Pelvic Medicine and Reconstructive Surgery, Allentown, PA, USA.
Vladimir EgorovArtann Laboratories, Trenton, NJ, USA.

Funding

Vaginal Tactile Imager for Pelvic Floor Biomechanical AssessmentR44AG034714 · NIA · ARTANN LABORATORIES, INC. · PI EGOROV, VLADIMIR · 2011 to 2014
$2.6M
Vaginal Tactile Imager for Pelvic Floor Biomechanical AssessmentSB1AG034714 · NIA · ARTANN LABORATORIES, INC. · PI SARVAZYAN, NOUNE · 2016 to 2017
$1.2M
NIA NIH HHS R44 AG034714NIA NIH HHS SB1 AG034714
6 · The paper itself

Abstract

backgroundFurther progress in restoring a woman's health may be possible if a patient with a damaged pelvic floor could undergo medical imaging and biomechanical diagnostic tests. The results of such tests could contribute to the analysis of multiple treatment options and suggest the optimal one for that patient.

aimTo develop a new approach for the biomechanical characterization of vaginal conditions, muscles, and connective tissues in the female pelvic floor.

methodsVaginal tactile imaging (VTI) allows biomechanical assessment of the soft tissue along the entire length of the anterior, posterior, and lateral vaginal walls at rest, with manually applied deflection pressures and with muscle contraction, muscle relaxation, and Valsalva maneuver. VTI allows a large body of measurements to evaluate individual variations in tissue elasticity, support defects, as well as pelvic muscle function. Presuming that 1) the female pelvic floor organs are suspended by ligaments against which muscles contract to open or close the outlets and 2) damaged ligaments weaken the support and may reduce the force of muscle contraction, we made an attempt to characterize multiple pelvic floor structures from VTI data.

resultsAll of the 138 women enrolled in the study were successfully examined with the VTI. The study subjects have had normal pelvic support or pelvic organ prolapse (stages I-IV). The average age of this group of subjects was 60±15 years. We transposed a set of 31 VTI parameters into a quantitative characterization of pelvic muscles and ligamentous structures. Interpretation of the acquired VTI data for normal pelvic floor support and prolapse conditions is proposed based on biomechanical assessment of the functional anatomy.

conclusionVaginal tactile imaging allows biomechanical characterization of female pelvic floor structures and tissues in vivo, which may help to optimize treatment of the diseased conditions such as prolapse, incontinence, atrophy, and some forms of pelvic pain.

Indexed as

biomechanicsdiagnosticfemale pelvic floorpelvic musclestactile imagingtissue elasticitytreatment

Identifiers

PMID28831274
PMCPMC5548279

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.