Evidence map›Paper›PMID 28831245›Full record

ReviewPatient preference and adherence2017

Medication adherence has an impact on disease activity in rheumatoid arthritis: a systematic review and meta-analysis.

Lin Li, Yafei Cui, Rulan Yin, Shengnan Chen, Qian Zhao, Haoyang Chen, Biyu Shen

Abstract readReview
In one paragraph

Review in Patient preference and adherence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lin LiDepartment of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.
Yafei CuiSchool of Nursing, Nantong University, Nantong, China.
Rulan YinDepartment of Emergency ICU, The First Affiliated Hospital of Soochow University, Suzhou, China.
Shengnan ChenSchool of Nursing, Nantong University, Nantong, China.
Qian ZhaoSchool of Nursing, Nantong University, Nantong, China.
Haoyang ChenDepartment of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.
Biyu ShenDepartment of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDisease activity of rheumatoid arthritis (RA) patients was often measured by the 28-joint count disease activity score (DAS-28), which consists of 28 swollen and tender joint counts, patient's assessment of disease activity (visual analog scale [VAS]) and erythrocyte sedimentation rate. C-reactive protein was also used to measure disease activity in RA patients. The aim was to explore the impact of medication adherence on disease activity in patients with RA.

methodsA systematic search was performed in major electronic databases (PubMed, Web of Science, the Cochrane Library, CNKI, VIP and Wan fang) to identify studies reporting medication adherence and disease activity in RA patients. Results were expressed as mean difference (MD) and 95% CI.

resultsA total of seven identified studies matched the inclusion criteria, reporting on a total of 1,963 adult RA patients in the analysis. The total score of DAS-28 was significantly lower in adherent patients than in nonadherent subjects (MD =-0.42, 95% CI [-0.80, -0.03],

conclusionThe study suggests that RA patients with higher medication adherence tended to have lower disease activity.

Indexed as

disease activitymedication adherencemeta-analysisrheumatoid arthritis

Identifiers

PMID28831245
PMCPMC5553350

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.