Evidence map›Paper›PMID 28831218›Full record

ArticleVeterinary world2017

Evaluation of crude larval protein and recombinant somatic protein 26/23 (rHcp26/23) immunization against

Omnia M Kandil, Khaled A Abdelrahman, Hatem A Shalaby, Seham H M Hendawy, Nadia M T Abu El Ezz, Somia A Nassar, James E Miller

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary world, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Immunity to gastrointestinal nematodes in ruminants: effector cell mechanisms and cytokines.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2018
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Omnia M KandilDepartment of Parasitology and Animal Diseases, National Research Centre, Dokki, P.O. Box 12622, Giza, Egypt.
Khaled A AbdelrahmanDepartment of Parasitology and Animal Diseases, National Research Centre, Dokki, P.O. Box 12622, Giza, Egypt.
Hatem A ShalabyDepartment of Parasitology and Animal Diseases, National Research Centre, Dokki, P.O. Box 12622, Giza, Egypt.
Seham H M HendawyDepartment of Parasitology and Animal Diseases, National Research Centre, Dokki, P.O. Box 12622, Giza, Egypt.
Nadia M T Abu El EzzDepartment of Parasitology and Animal Diseases, National Research Centre, Dokki, P.O. Box 12622, Giza, Egypt.
Somia A NassarDepartment of Parasitology and Animal Diseases, National Research Centre, Dokki, P.O. Box 12622, Giza, Egypt.
James E MillerDepartment of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA.
National Research Centre · EGLouisiana State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to evaluate the potential possibility of crude larval and recombinant (rHcp26/23) antigens of MATERIALS AND

methodsA total of 21 lambs were divided into five groups. Lambs were immunized with larval and recombinant (rHcp26/23) proteins at day 0 and day 14 and after that challenged with 5000 infective larvae of

resultsFecal egg count reduction taking after challenge for rHcp26/23 and larval antigens was 92.2% and 38.2%, respectively, compared with the positive control group. Vaccine incited protection in rHcp26/23 and larval immunization was reflected in significant (p<0.05) decreases in worm burden; 59.9% and 40.1%, respectively.

conclusionRecombinant rHcp26/23 vaccine induced a partial immune response and had immune-protective effect against sheep hemonchosis.

Indexed as

antigenHaemonchus contortusimmunizationlarvalrHcp26/23sheep

Identifiers

PMID28831218
PMCPMC5553143
OpenAlexW2727168470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.