ArticleScientific reports2017
Fungal lifestyle reflected in serine protease repertoire.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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68 citing papers in PubMed.
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- The proteome study of germinated Puccinia triticina urediniospores reveals a novel effector protein required for virulence.Scientific reports · 2026Article
- Article
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- Organic matter degradation by oceanic fungi differs between polar and non-polar waters.Nature communications · 2025Article
- Harnessing Nutritional Niches to Explore Fungus-Animal Symbioses.Ecology letters · 2025Review
- α/β Hydrolases: Toward Unraveling Entangled Classification.Proteins · 2025Article
- Functional genome analysis reveals that serine carboxypeptidaseFrontiers in plant science · 2025Article
- A Draft Genome Assembly for the Neglected Tropical Fungal Disease Pathogen Emarellia grisea and Comparison to Other Pleosporalean Agents Causing Eumycetoma in Humans.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Phosphite inhibitsFrontiers in microbiology · 2025Article
- An acidophilic fungus promotes prey digestion in a carnivorous plant.Nature microbiology · 2024Article
- Identification of Potential New Genes Related to the SREBP Pathway inBiomolecules · 2024Article
- First Insight into the Degradome ofInternational journal of molecular sciences · 2024Article
- Influence of Salinity on the Extracellular Enzymatic Activities of Marine Pelagic Fungi.Journal of fungi (Basel, Switzerland) · 2024Article
- The genome of Salmacisia buchloëana, the parasitic puppet master pulling strings of sexual phenotypic monstrosities in buffalograss.G3 (Bethesda, Md.) · 2024Article
- Genome sequencing and molecular networking analysis of the wild fungus Anthostomella pinea reveal its ability to produce a diverse range of secondary metabolites.Fungal biology and biotechnology · 2024Article
- Genome-resolved metatranscriptomics reveals conserved root colonization determinants in a synthetic microbiota.Nature communications · 2023Article
- The expression landscape and pangenome of long non-coding RNA in the fungal wheat pathogenMicrobial genomics · 2023Article
- Large-scale genomic analyses with machine learning uncover predictive patterns associated with fungal phytopathogenic lifestyles and traits.Scientific reports · 2023Article
8 more citing papers are in PubMed but not listed here.
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Fungi are able to switch between different lifestyles in order to adapt to environmental changes. Their ecological strategy is connected to their secretome as fungi obtain nutrients by secreting hydrolytic enzymes to their surrounding and acquiring the digested molecules. We focus on fungal serine proteases (SPs), the phylogenetic distribution of which is barely described so far. In order to collect a complete set of fungal proteases, we searched over 600 fungal proteomes. Obtained results suggest that serine proteases are more ubiquitous than expected. From 54 SP families described in MEROPS Peptidase Database, 21 are present in fungi. Interestingly, 14 of them are also present in Metazoa and Viridiplantae - this suggests that, except one (S64), all fungal SP families evolved before plants and fungi diverged. Most representatives of sequenced eukaryotic lineages encode a set of 13-16 SP families. The number of SPs from each family varies among the analysed taxa. The most abundant are S8 proteases. In order to verify hypotheses linking lifestyle and expansions of particular SP, we performed statistical analyses and revealed previously undescribed associations. Here, we present a comprehensive evolutionary history of fungal SP families in the context of fungal ecology and fungal tree of life.
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