Evidence map›Paper›PMID 28831098›Full record

ArticleScientific reports2017

RNA-Seq analysis on chicken taste sensory organs: An ideal system to study organogenesis.

Xiaogang Cui, Brett Marshall, Ning Shi, Shi-You Chen, Romdhane Rekaya, Hong-Xiang Liu

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Selection signature analysis revealsArchives animal breeding · 2023
    Article
  4. Bitter Taste Perception in Chickens.The journal of poultry science · 2022
    Article
  5. Article
  6. Article
  7. Early taste buds are from ShhBiochemical and biophysical research communications · 2019
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaogang CuiRegenerative Bioscience Center, University of Georgia, Athens, GA, USA.
Brett MarshallRegenerative Bioscience Center, University of Georgia, Athens, GA, USA.
Ning ShiDepartment of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Shi-You ChenDepartment of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Romdhane RekayaDepartment of Animal and Dairy Science, College of Agricultural and Environmental Sciences, University of Georgia, Athens, GA, USA.
Hong-Xiang LiuRegenerative Bioscience Center, University of Georgia, Athens, GA, USA. lhx@uga.edu.

Funding

Taste organs: formation and regulationR01DC012308 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, HONGXIANG · 2013 to 2017
$1.9M
NIDCD NIH HHS R01 DC012308
6 · The paper itself

Abstract

RNA-Seq is a powerful tool in transcriptomic profiling of cells and tissues. We recently identified many more taste buds than previously appreciated in chickens using molecular markers to stain oral epithelial sheets of the palate, base of oral cavity, and posterior tongue. In this study, RNA-Seq was performed to understand the transcriptomic architecture of chicken gustatory tissues. Interestingly, taste sensation related genes and many more differentially expressed genes (DEGs) were found between the epithelium and mesenchyme in the base of oral cavity as compared to the palate and posterior tongue. Further RNA-Seq using specifically defined tissues of the base of oral cavity demonstrated that DEGs between gustatory (GE) and non-gustatory epithelium (NGE), and between GE and the underlying mesenchyme (GM) were enriched in multiple GO terms and KEGG pathways, including many biological processes. Well-known genes for taste sensation were highly expressed in the GE. Moreover, genes of signaling components important in organogenesis (Wnt, TGFβ/ BMP, FGF, Notch, SHH, Erbb) were differentially expressed between GE and GM. Combined with other features of chicken taste buds, e.g., uniquely patterned array and short turnover cycle, our data suggest that chicken gustatory tissue provides an ideal system for multidisciplinary studies, including organogenesis and regenerative medicine.

Indexed as

OrganogenesisAnimalsChick EmbryoChickensGene Expression ProfilingMesodermOrgan SpecificityPalateSequence Analysis, RNASignal TransductionTaste BudsTongue

Identifiers

PMID28831098
PMCPMC5567234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.