ArticleScientific reports2017
Discrimination of three types of homopolymers in single-stranded DNA with solid-state nanopores through external control of the DNA motion.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- The Road Toward Nanopore Sequencing of Glycosaminoglycans.Handbook of experimental pharmacology · 2025Review
- Angular-Inertia Regulated Stable and Nanoscale Sensing of Single Molecules Using Nanopore-In-A-Tube.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- In-tube micro-pyramidal silicon nanopore for inertial-kinetic sensing of single molecules.Nature communications · 2024Article
- Exploring single-molecule interactions: heparin and FGF-1 proteins through solid-state nanopores.Nanoscale · 2024Article
- Fast Fabrication Nanopores on a PMMA Membrane by a Local High Electric Field Controlled Breakdown.Sensors (Basel, Switzerland) · 2024Article
- Article
- Polymer Translocation and Nanopore Sequencing: A Review of Advances and Challenges.International journal of molecular sciences · 2023Review
- Application of Solid-State Nanopore in Protein Detection.International journal of molecular sciences · 2020Review
- Controlling DNA Translocation Through Solid-state Nanopores.Nanoscale research letters · 2020Review
- Solid-state nanopores towards single-molecule DNA sequencing.Journal of human genetics · 2020Review
- Stable fabrication of a large nanopore by controlled dielectric breakdown in a high-pH solution for the detection of various-sized molecules.Scientific reports · 2019Article
- High bandwidth approaches in nanopore and ion channel recordings - A tutorial review.Analytica chimica acta · 2019Review
- Slowing down DNA translocation velocity using a LiCl salt gradient and nanofiber mesh.European biophysics journal : EBJ · 2019Article
- Colloquium: Ionic phenomena in nanoscale pores through 2D materials.Reviews of modern physics · 2019Article
- Two-step breakdown of a SiN membrane for nanopore fabrication: Formation of thin portion and penetration.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To achieve DNA sequencing with solid-state nanopores, the speed of the DNA in the nanopore must be controlled to obtain sequence-specific signals. In this study, we fabricated a nanopore-sensing system equipped with a DNA motion controller. DNA strands were immobilized on a Si probe, and approach of this probe to the nanopore vicinity could be controlled using a piezo actuator and stepper motor. The area of the Si probe was larger than the area of the membrane, which meant that the immobilized DNA could enter the nanopore without the need for the probe to scan to determine the location of the nanopore in the membrane. We demonstrated that a single-stranded DNA could be inserted into and removed from a nanopore in our experimental system. The number of different ionic-current levels observed while DNA remained in the nanopore corresponded to the number of different types of homopolymers in the DNA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.