Evidence map›Paper›PMID 28830977›Full record

ArticlePhysiological reports2017

Lack of direct effect of adiponectin on vascular smooth muscle cell BK

Rachael Baylie, Majid Ahmed, Adrian D Bonev, David C Hill-Eubanks, Thomas J Heppner, Mark T Nelson, Adam S Greenstein

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rachael BaylieDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Majid AhmedDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Adrian D BonevDepartment of Pharmacology, University of Vermont, Burlington, Vermont.
David C Hill-EubanksDepartment of Pharmacology, University of Vermont, Burlington, Vermont.
Thomas J HeppnerDepartment of Pharmacology, University of Vermont, Burlington, Vermont.
Mark T NelsonDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Adam S GreensteinDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK adam.greenstein@manchester.ac.uk.
University of Vermont · USManchester Academic Health Science Centre · GBUniversity of Manchester · GB

Funding

Impact of SAH on Parenchymal Arterioles and Neurovascular CouplingP01HL095488 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2010 to 2014
$11.4M
REGULATION OF CEREBRAL ARTERY DILATIONR01HL044455 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI NELSON, MARK T · 1991 to 2010
$3.9M
Ca2+ Sparks and Urinary Bladder Smooth Muscle ExcitabilityR37DK053832 · NIDDK · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2008 to 2017
$3.4M
CA++ SPARKS &URINARY BLADDER SMOOTH MUSCLE EXCITABILITYR01DK053832 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI NELSON, MARK T · 1998 to 2006
$2.0M
Endothelial KCa channels, Ca2+ signaling & arteriolar function in the brainR01HL098243 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2010 to 2010
$269k
LIMITATIONS OF CORONARY AUTOREGULATORY RESPONSESK08HL001168 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 1985 to 1987
–
RENAL MOLECULAR BIOLOGYZ01HL001281 · NHLBI · HEART, LUNG, AND BLOOD INSTITUTE · PI GARCIA-PEREZ, A · 1986 to 1987
–
British Heart Foundation FS/11/68/28821British Heart Foundation FS/12/81/29882British Heart Foundation FS/14/26/30767British Heart Foundation PG/15/109/31931NHLBI NIH HHS P01 HL095488NHLBI NIH HHS R01 HL044455NHLBI NIH HHS R01 HL098243NIDDK NIH HHS R01 DK053832NIDDK NIH HHS R37 DK053832
6 · The paper itself

Abstract

The aim of this study was to investigate mechanisms by which adiponectin influences vascular Ca

Indexed as

Calcium SignalingVasoconstrictionAdiponectinAnimalsArteriesCells, CulturedLarge-Conductance Calcium-Activated Potassium ChannelsMiceMice, Inbred C57BLMuscle ContractionMuscle, Smooth, VascularMyocytes, Smooth MuscleAdiponectinLarge-Conductance Calcium-Activated Potassium ChannelsAdiponectinBK channelcalciumperivascular adipose tissue

Identifiers

PMID28830977
PMCPMC5582259
OpenAlexW2626988450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.