Evidence map›Paper›PMID 28830930›Full record

ArticleThe Journal of biological chemistry2017

Increased heme synthesis in yeast induces a metabolic switch from fermentation to respiration even under conditions of glucose repression.

Tiantian Zhang, Pengli Bu, Joey Zeng, Ales Vancura

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Single-cell analyses identify independent aging processes that compete to determine cellular fate in budding yeast.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Secreted Frizzled-related proteins in animal development.Histochemistry and cell biology · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Genes · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. RewiringMetabolic engineering communications · 2024
    Article
  16. Article
  17. Lifespan regulation by targeting heme signaling in yeast.bioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tiantian ZhangFrom the Department of Biological Sciences, St. John's University, Queens, New York 11439.
Pengli BuFrom the Department of Biological Sciences, St. John's University, Queens, New York 11439.
Joey ZengFrom the Department of Biological Sciences, St. John's University, Queens, New York 11439.
Ales VancuraFrom the Department of Biological Sciences, St. John's University, Queens, New York 11439 vancuraa@stjohns.edu.
St. John's University · US

Funding

Transcriptional Regulation and MetabolismR15GM120710 · NIGMS · ST. JOHN'S UNIVERSITY · PI VANCURA, ALES · 2016 to 2016
$495k
NIGMS NIH HHS R15 GM120710
6 · The paper itself

Abstract

Regulation of mitochondrial biogenesis and respiration is a complex process that involves several signaling pathways and transcription factors as well as communication between the nuclear and mitochondrial genomes. Under aerobic conditions, the budding yeast

Indexed as

FermentationGene Expression Regulation, FungalGlucoseHemeOxygen ConsumptionSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsGlucoseHemeSaccharomyces cerevisiae ProteinsTranscription FactorsHap1HAP complexhememetabolic regulationmetabolic reprogrammingmetabolismoxidative phosphorylationrespirationtranscriptiontricarboxylic acid cycle (TCA cycle) (Krebs cycle)

Identifiers

PMID28830930
PMCPMC5641876
OpenAlexW2748015212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.