Evidence map›Paper›PMID 28830902›Full record

ArticleBMJ case reports2017

Zoster vaccine-associated primary varicella infection in an immunocompetent host.

Kaoru Harada, Henry Heaton, Jason Chen, Marietta Vazquez, Jaimie Meyer

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaoru HaradaDepartment of Internal Medicine, Yale-New Haven Hospital, New Haven, Connecticut, USA.
Henry HeatonDepartment of Dermatology, Yale-New Haven Hospital, New Haven, Connecticut, USA.
Jason ChenDepartment of Pathology & Cell Biology, Columbia University College of Physicians & Surgeons, New York, New York, USA.
Marietta VazquezDepartment of Pediatrics, Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.
Jaimie MeyerDepartment of Medicine, Infectious Diseases, AIDS Program, Yale University School of Medicine, New Haven, Connecticut, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Evaluating and Improving HIV Outcomes in Community-Based Women who Interface withK23DA033858 · NIDA · YALE UNIVERSITY · PI MEYER, JAIMIE · 2012 to 2016
$821k
Doris Duke Charitable Foundation 2017080NCATS NIH HHS UL1 TR001863NIDA NIH HHS K23 DA033858
6 · The paper itself

Abstract

A 64-year-old immunocompetent man developed a widespread pruritic and vesicular rash 2 weeks after receiving the zoster vaccine (Zostavax). He had fever, bandaemia with normal total white blood cell count and mild transaminitis. PCR testing of serum and skin was positive for varicella zoster virus (VZV), while serum VZV IgG was negative. The analysis of single nucleotide polymorphism by PCR and sequencing from the skin swab was consistent with the vaccine strain. The patient received 1 week of intravenous acyclovir and was discharged after all lesions had crusted. He continues to do well on follow-up with no significant complications.

Indexed as

ImmunocompetenceAcyclovirAntiviral AgentsDiagnosis, DifferentialFeverHerpes Zoster VaccineHumansInfusions, IntravenousMaleMiddle AgedVaricella Zoster Virus InfectionAcyclovirAntiviral AgentsHerpes Zoster Vaccineimmunological products and vaccinessafetyskinunwanted effects / adverse reactionsvaccination/immunisation

Identifiers

PMID28830902
PMCPMC5624100

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.