ArticleBMC research notes2017
Pertussis outbreak investigation of Mekdela district, South Wollo zone, Amhara region, North-West Ethiopia.
Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Attack Rate, Case Fatality Rate and Predictors of Pertussis Outbreak During Pertussis Outbreak Investigation in Ethiopia: Systematic Review and Meta-Analysis.Journal of epidemiology and global health · 2024Pooled it
- Pertussis: a retrospective analysis of cases observed in Mersin Türkiye, 2020 to 2024 evaluation of pertussis cases.BMC infectious diseases · 2026Article
- Pertussis outbreak investigation, associated risk factors, and evaluation of intervention effectiveness in Sayient Woreda, South Wollo Zone, Northwest Ethiopia: A case-control study.SAGE open medicine · 2026Article
- Epidemiological investigation of a pertussis outbreak among schoolchildren in Burkina Faso, 2019.BMC research notes · 2025Article
- Global burden of pertussis in 204 countries and territories, from 1990 to 2019: results from the Global Burden of Disease Study 2019.BMC public health · 2024Article
- Pertussis outbreak investigation in Likimsa-BokoreThe Pan African medical journal · 2024Article
- Article
- Bordetella pertussis in School-Age Children, Adolescents, and Adults: A Systematic Review of Epidemiology, Burden, and Mortality in Africa.Infectious diseases and therapy · 2021Review
- An epidemiological investigation of the 2019 suspected pertussis outbreak in northwestern Nigeria.SAGE open medicine · 2021Article
- Pertussis outbreak in southern Ethiopia: challenges of detection, management, and response.BMC public health · 2020Article
- The situation of vaccines for the prevention of infections in adults: An opinion paper on the situation in Spain.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019Article
- Pertussis outbreak investigation in Janamora district, Amhara Regional State, Ethiopia: a case-control study.The Pan African medical journal · 2019Article
- Outbreak investigation of pertussis in an elementary school: a case-control study among vaccinated students.Clinical and experimental vaccine research · 2018Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPertussis is a highly contagious respiratory illness caused by Bordetella pertussis. It is one of the most common vaccine-preventable bacterial infections that affects all susceptible individuals, regardless of age. Investigation was done to verify the existence of an outbreak and to identify associated risk factors contributed for the occurrence of an outbreak in Tork and Warkaye villages of Mekdela district.
methodsUnmatched community based case control and descriptive cross sectional investigation were conducted with one to two ratios. We used structured questionnaire to collect data from cases and controls.
resultsA total of 215 cases and eight deaths were identified with an overall attack rate of 1.3 per 1000 population. The mean age of the cases was 3.7 years which was ranged from 3 months to 45 years. The more affected groups were females. On multivariate logistic regression analysis, the risk factor that remained independently statically significant associated with developing pertussis was presence of infected person in the family AOR (adjusted odds ratio): 5.859, (95% CI 2.526-13.589). But previously sick with pertussis AOR: 0.053, (95% CI 0.006-0.460) and receiving full dose of vaccine AOR: 0.256, (95% CI 0.080-0.818) were remained as protective factors from pertussis infection.
conclusionsThe suspected pertussis outbreak was occurred in remote pocket villages/kebeles of Mekdela district. Routine immunization was not given regularly and functional refrigerators were not available in the health posts. Routine immunization services and treatment of infected patients with appropriate antibiotics should be intensified.
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