Evidence map›Paper›PMID 28830457›Full record

ArticlePediatric rheumatology online journal2017

Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort.

Jaime Guzman, Tristan Kerr, Leanne M Ward, Jinhui Ma, Kiem Oen, Alan M Rosenberg, Brian M Feldman, Gilles Boire, Kristin Houghton, Paul Dancey and 42 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric rheumatology online journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Guideline
  4. Trial
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Growth and puberty in children with juvenile idiopathic arthritis.Pediatric rheumatology online journal · 2021
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Metabolic syndrome in adults with a history of juvenile arthritis.Open access rheumatology : research and reviews · 2018
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

52 authors at 18 institutions in 2 countries.

Jaime GuzmanFrom British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada. jguzman@cw.bc.ca.ORCID http://orcid.org/0000-0001-8977-2581
Tristan KerrDivision of Pediatric Rheumatology, BC Children's Hospital, 4500 Oak St, Suite K4-122, Vancouver, BC, V6H 3N1, Canada.
Leanne M WardChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.
Jinhui MaChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.
Kiem OenDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
Alan M RosenbergRoyal University Hospital and University of Saskatchewan, Saskatoon, Canada.
Brian M FeldmanHospital for Sick Children and University of Toronto, Toronto, Canada.
Gilles BoireCentre Hospitalier Universitaire de Sherbrooke and Université de Sherbrooke, Sherbrooke, Canada.
Kristin HoughtonFrom British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada.
Paul DanceyJaneway Children's Health and Rehabilitation Centre and Memorial University, Saint John, 's, Canada.
Rosie ScuccimarriMcGill University Health Centre and McGill University, Montreal, Canada.
Alessandra BrunsCentre Hospitalier Universitaire de Sherbrooke and Université de Sherbrooke, Sherbrooke, Canada.
Adam M HuberIWK Health Centre and Dalhousie University, Halifax, Canada.
Karen Watanabe DuffyChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.
Natalie J ShiffShands Children's Hospital and University of Florida, Gainesville, USA.
Roberta A BerardLondon Health Sciences Centre and Western University, London, Canada.
Deborah M LevyHospital for Sick Children and University of Toronto, Toronto, Canada.
Elizabeth StringerIWK Health Centre and Dalhousie University, Halifax, Canada.
Kimberly MorishitaFrom British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada.
Nicole JohnsonAlberta Children's Hospital and University of Calgary, Calgary, Canada.
David A CabralFrom British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada.
Maggie LarchéMcMaster University, Hamilton, Canada.
Ross E PettyFrom British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada.
Ronald M LaxerHospital for Sick Children and University of Toronto, Toronto, Canada.
Earl SilvermanHospital for Sick Children and University of Toronto, Toronto, Canada.
Paivi MiettunenAlberta Children's Hospital and University of Calgary, Calgary, Canada.
Anne-Laure ChetailleCentre Hospitalier Universitaire de Laval and Université Laval, Quebec, Canada.
Elie HaddadCentre Hospitalier Universitaire Ste. Justine and Université de Montréal, Montréal, Canada.
Lynn SpiegelHospital for Sick Children and University of Toronto, Toronto, Canada.
Stuart E TurveyFrom British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada.
Heinrike SchmelingAlberta Children's Hospital and University of Calgary, Calgary, Canada.
Bianca LangIWK Health Centre and Dalhousie University, Halifax, Canada.
Janet EllsworthStollery Children's Hospital and University of Alberta, Edmonton, Canada.
Suzanne E RamseyIWK Health Centre and Dalhousie University, Halifax, Canada.
Johannes RothChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.
Sarah CampilloMcGill University Health Centre and McGill University, Montreal, Canada.
Susanne BenselerAlberta Children's Hospital and University of Calgary, Calgary, Canada.
Gaëlle ChédevilleMcGill University Health Centre and McGill University, Montreal, Canada.
Rayfel SchneiderHospital for Sick Children and University of Toronto, Toronto, Canada.
Shirley M L TseHospital for Sick Children and University of Toronto, Toronto, Canada.
Roxana BolariaDepartment of Pediatrics University of British Columbia, Vancouver, Canada.
Katherine GrossDepartment of Pediatrics University of British Columbia, Vancouver, Canada.
Debbie FeldmanUniversité de Montréal, Montréal, Canada.
Bonnie CameronHospital for Sick Children and University of Toronto, Toronto, Canada.
Roman JurencakChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.
Jean DorvalCentre Hospitalier Universitaire de Laval and Université Laval, Quebec, Canada.
Claire LeBlancMcGill University Health Centre and McGill University, Montreal, Canada.
Claire St CyrCentre Hospitalier Universitaire Ste. Justine and Université de Montréal, Montréal, Canada.
Michele GibbonChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.
Rae S M YeungHospital for Sick Children and University of Toronto, Toronto, Canada.
Ciarán M DuffyChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.
Lori B TuckerFrom British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada.
University of British Columbia · CAUniversity of Toronto · CAUniversity of Ottawa · CADalhousie University · CAMcGill University Health Centre · CAUniversity of Calgary · CACentre hospitalier de l'Université Laval · CACentre Hospitalier Universitaire Sainte-Justine · CAUniversité de Sherbrooke · CABC Children's Hospital · CAMcMaster University · CAMemorial University of Newfoundland · CARoyal University Hospital · CAUF Health Shands Hospital · USUniversité de Montréal · CAUniversity of Alberta · CAUniversity of Manitoba · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith modern treatments, the effect of juvenile idiopathic arthritis (JIA) on growth may be less than previously reported. Our objective was to describe height, weight and body mass index (BMI) development in a contemporary JIA inception cohort.

methodsCanadian children newly-diagnosed with JIA 2005-2010 had weight and height measurements every 6 months for 2 years, then yearly up to 5 years. These measurements were used to calculate mean age- and sex-standardized Z-scores, and estimate prevalence and cumulative incidence of growth impairments, and the impact of disease activity and corticosteroids on growth.

resultsOne thousand one hundred forty seven children were followed for median 35.5 months. Mean Z-scores, and the point prevalence of short stature (height < 2.5th percentile, 2.5% to 3.4%) and obesity (BMI > 95th percentile, 15.8% to 16.4%) remained unchanged in the whole cohort. Thirty-three children (2.9%) developed new-onset short stature, while 27 (2.4%) developed tall stature (>97.5th percentile). Children with systemic arthritis (n = 77) had an estimated 3-year cumulative incidence of 9.3% (95%CI: 4.3-19.7) for new-onset short stature and 34.4% (23-49.4) for obesity. Most children (81.7%) received no systemic corticosteroids, but 1 mg/Kg/day prednisone-equivalent maintained for 6 months corresponded to a drop of 0.64 height Z-scores (0.56-0.82) and an increase of 0.74 BMI Z-scores (0.56-0.92). An increase of 1 in the 10-cm physician global assessment of disease activity maintained for 6 months corresponded to a drop of 0.01 height Z-scores (0-0.02).

conclusionsMost children in this modern JIA cohort grew and gained weight as children in the general population. About 1 in 10 children who had systemic arthritis, uncontrolled disease and/or prolonged corticosteroid use, had increased risk of growth impairment.

Indexed as

AdolescentAnthropometryArthritis, JuvenileCanadaChildChild, PreschoolFemaleFollow-Up StudiesGlucocorticoidsGrowth DisordersHumansIncidenceMalePrevalenceProspective StudiesWeight GainGlucocorticoidsCorticosteroidsGrowthJuvenile arthritisObesity

Identifiers

PMID28830457
PMCPMC5567720
OpenAlexW2745482549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.