ArticleBMC ophthalmology2017
Hydrophilic intraocular lens opacification after posterior lamellar keratoplasty - a material analysis with special reference to optical quality assessment.
Article in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 62 citations in OpenAlex.
- Epithelial cell proliferation on anterior surface of intraocular lens after Descemet stripping automated endothelial keratoplasty (DSAEK) surgery: a case report.BMC ophthalmology · 2026Article
- Descemet membrane endothelial keratoplasty combined with secondary sulcus hydrophobic intraocular lens implantation.American journal of ophthalmology case reports · 2025Article
- Review of the Literature: Surgery Indications for Fuchs' Endothelial Corneal Dystrophy.Journal of clinical medicine · 2025Review
- Impact of Calcium and Phosphorus Levels on Optical Deterioration in Primary and Secondary Intraocular Lens Calcification.Translational vision science & technology · 2024Article
- Intraocular lens calcification in a patient with Ehlers-Danlos syndrome.American journal of ophthalmology case reports · 2024Article
- Higher phosphate concentrations as in aqueous humor of diabetic patients increase intraocular lens calcification.BMC ophthalmology · 2024Article
- Material Analysis of Explanted Calcified Silicone Intraocular Lenses in Association with Asteroid Hyalosis.Ophthalmology and therapy · 2024Article
- The Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: report 16, influence of remuneration model on choice of intraocular lens in the UK.Eye (London, England) · 2023Article
- [Hydrophobic surface properties of hydrophilic acrylic lenses do not protect against calcification].Die Ophthalmologie · 2023Article
- Clinical Characteristics of Patients with Intraocular Lens Calcification after Pars Plana Vitrectomy.Diagnostics (Basel, Switzerland) · 2023Article
- Descemet membrane endothelial keratoplasty: Update on preoperative considerations, surgical techniques, and outcomes.Indian journal of ophthalmology · 2022Review
- Development of a standardized in vitro model to reproduce hydrophilic acrylic intraocular lens calcification.Scientific reports · 2022Article
- Outcomes of four-point suture fixated and two-point sutureless posterior chamber IOLs combined with pars plana vitrectomy.BMC ophthalmology · 2022Article
- [Material properties of intraocular lenses: are there patient-relevant differences?]Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021Article
- Effects of uncomplicated Descemet membrane endothelial keratoplasty on the central retinal thickness.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Visualization of Forward Light Scatter in Opacified Intraocular Lenses and Straylight Assessment.Diagnostics (Basel, Switzerland) · 2021Article
- Laboratory evaluation of higher-order aberrations and light scattering in explanted opacified intraocular lenses.Eye and vision (London, England) · 2021Article
- A narrative review of intraocular lens opacifications: update 2020.Annals of translational medicine · 2020Review
- Revaluating the relationship between keratoplasty and intraocular lenses.Eye (London, England) · 2020Article
- Physicochemical Analysis of Sediments Formed on the Surface of Hydrophilic Intraocular Lens after Descemet's Stripping Endothelial Keratoplasty.Materials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaboratory analysis and optical quality assessment of explanted hydrophilic intraocular lenses (IOLs) with clinically significant opacification after posterior lamellar keratoplasty (DMEK and DSAEK).
methodsThirteen opacified IOLs after posterior lamellar keratoplasty, 8 after descemet stripping automated endothelial keratoplasty (DSAEK), 3 after descemet membrane endothelial keratoplasty (DMEK) and 2 after both DSAEK and DMEK were analysed in our laboratory. Analyses included optical bench assessment for optical quality, light microscopy, scanning electron microscopy (SEM) and energy dispersive X-Ray spectroscopy (EDS).
resultsIn all IOLs the opacification was caused by a thin layer of calciumphosphate that had accumulated underneath the anterior optical surface of the IOLs in the area spared by the pupil/anterior capsulorhexis. The calcifications lead to a significant deterioration of the modulation transfer function across all spatial frequencies of the affected IOLs.
conclusionsThe instillation of exogenous material such as air or gas into the anterior chamber increases the risk for opacification of hydrophilic IOLs irrespective of the manufacturer or the exact composition of the hydrophilic lens material. It is recommended to avoid the use of hydrophilic acrylic IOLs in patients with endothelial dystrophy that will likely require procedures involving the intracameral instillation of air or gas, such as DMEK or DS(A)EK.
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