ArticleCanadian journal of psychiatry. Revue canadienne de psychiatrie2018
Antipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities.
Article in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Pharmacogenomic Studies in Intellectual Disabilities and Autism Spectrum Disorder: A Systematic Review.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2021Pooled it
- Association of Focused Medication Review With Optimization of Psychotropic Drug Prescribing: A Systematic Review and Meta-analysis.JAMA network open · 2018Pooled it
- Primary care of adults with intellectual and developmental disabilities: 2018 Canadian consensus guidelines.Canadian family physician Medecin de famille canadien · 2018Guideline
- Prevalence of Psychotropic Use and Psychotropic Polypharmacy in a Finnish National Cohort of Persons With Intellectual Disabilities.Journal of intellectual disability research : JIDR · 2026Observational
- A Rapid Mapping Review of Medication Burden in Adults with an Intellectual Disability: What We Know and What We Do Not Know.Drug, healthcare and patient safety · 2026Review
- Prescriptions for Antipsychotics: Youth with Intellectual/Developmental Disabilities Compared to Youth without Intellectual/Developmental Disabilities.Journal of autism and developmental disorders · 2025Article
- Prevalence of Psychotropic Medication Use and Psychotropic Polypharmacy in Autistic Adults With or Without Intellectual Disability.Journal of autism and developmental disorders · 2025Article
- Exploring Connections Between Living Situations and Antipsychotic Prescribing Practices for People With Intellectual Disabilities.Psychiatric research and clinical practice · 2025Article
- Discordance Between Psychiatric Diagnoses and Medication Use in Children and Adults With Autism Presenting in Crisis.Focus (American Psychiatric Publishing) · 2024Article
- Adverse events and contradictory effects of benzodiazepine in a case with intellectual disability and challenging behaviour.Journal of intellectual disabilities : JOID · 2024Article
- Antipsychotic-induced weight gain: exploring the role of psychiatrists in managing patients' physical health - challenges, current options and direction for future care.BJPsych bulletin · 2024Article
- Article
- Withdrawing Antipsychotics for Challenging Behaviours in Adults with Intellectual Disabilities: Experiences and Views of Prescribers.International journal of environmental research and public health · 2022Article
- Psychotropic Medication Monitoring in a Human Services Organization for Children with Autism Spectrum Disorder: Description and Evaluation of Interdisciplinary Team Review.Behavior analysis in practice · 2022Article
- Psychotropic drugs intake in people aging with intellectual disability: Prevalence and predictors.Journal of applied research in intellectual disabilities : JARID · 2022Article
- Differentiating tardive dyskinesia: a video-based review of antipsychotic-induced movement disorders in clinical practice.CNS spectrums · 2022Review
- Demonstrating an Analyses of Clinical Data Evaluating Psychotropic Medication Reductions and the ACHIEVE! Program in Adolescents with Severe Problem Behavior.Perspectives on behavior science · 2022Article
- Changes over a decade in psychotropic prescribing for people with intellectual disabilities: prospective cohort study.BMJ open · 2020Article
- Recognition and Treatment of Tardive Dyskinesia in Individuals with Intellectual Disability.Case reports in psychiatry · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAntipsychotic use is controversial in the management of adults with intellectual and developmental disabilities (IDD) because of inconclusive evidence for efficacy in the absence of a comorbid psychiatric condition, and substantial concerns about adverse effects. We aimed to characterize antipsychotic use among Ontario adults with IDD and compare profiles of those with and without a documented psychiatric diagnosis.
methodThis population-based study included 51,881 adults with IDD under 65 y as of April 2010 receiving provincial drug benefits in Ontario who were followed until March 2016 to identify those dispensed at least one antipsychotic medication. Profiles of those with and without a psychiatric diagnosis were compared.
resultsOverall, 39.2% of adults ( n = 20,316) were dispensed an antipsychotic medication, which increased to 56.4% in a subcohort residing in group homes. Almost one-third (28.91%) of people prescribed an antipsychotic medication did not have a documented psychiatric diagnosis. Those without a psychiatric diagnosis differed considerably from those with a diagnosis. In particular, those without a psychiatric diagnosis were older, less likely to have used antidepressants or benzodiazepines in the year before, and less likely to have used ambulatory and acute care.
conclusionsAntipsychotic use in IDD is common, and occurs frequently without a psychiatric diagnosis. Attention toward how antipsychotics are prescribed and monitored for people with IDD in Canada is warranted to ensure appropriate prescribing.
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Registered trials
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