ArticleJournal of experimental botany2017
Transcriptional regulatory network of WOX11 is involved in the control of crown root development, cytokinin signals, and redox in rice.
Article in Journal of experimental botany, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 94 citations in OpenAlex.
- Article
- INDETERMINATE DOMAIN 9 negatively regulates rice crown root development.Frontiers in plant science · 2026Article
- WOX11-OsPRX130 module confers rice drought tolerance by maintaining ROS homeostasis in rice root.Rice (New York, N.Y.) · 2025Article
- DNA methylation dynamics play crucial roles in shaping the distinct transcriptomic profiles for different root-type initiation in rice.Genome biology · 2025Article
- Genome-Wide Identification ofPlants (Basel, Switzerland) · 2025Article
- Exploring Hormonal Pathways and Gene Networks in Crown Root Formation Under Stress Conditions: An Update.Plants (Basel, Switzerland) · 2025Review
- Transcription factors WOX11 and LBD16 function with histone demethylase JMJ706 to control crown root development in rice.The Plant cell · 2024Article
- OsUGE2 Regulates Plant Growth through Affecting ROS Homeostasis and Iron Level in Rice.Rice (New York, N.Y.) · 2024Article
- BpWOX11 promotes adventitious root formation in Betula pendula.BMC plant biology · 2024Article
- SLG2 specifically regulates grain width through WOX11-mediated cell expansion control in rice.Plant biotechnology journal · 2023Article
- ROS-stimulated protein lysine acetylation is required for crown root development in rice.Journal of advanced research · 2023Article
- Transcriptome and Co-Expression Network Analysis Reveals the Molecular Mechanism of Rice Root Systems in Response to Low-Nitrogen Conditions.International journal of molecular sciences · 2023Article
- WOX11: the founder of plant organ regeneration.Cell regeneration (London, England) · 2023Review
- Genome-wide identification of NAC transcription factors and regulation of monoterpenoid indole alkaloid biosynthesis inFrontiers in plant science · 2023Article
- WUSCHEL-related homeobox genes cooperate with cytokinin to promote bulbil formation in Lilium lancifolium.Plant physiology · 2022Article
- Genome-Wide Analysis of theGenes · 2022Article
- Article
- Transcriptome analysis reveals the regulatory mechanism by whichHorticulture research · 2022Article
- Characterization of walnutFrontiers in plant science · 2022Article
- PagWOX11/12a activates PagCYP736A12 gene that facilitates salt tolerance in poplar.Plant biotechnology journal · 2021Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rice root system is mainly composed of post-embryonic shoot-borne roots called crown roots. WOX11, encoding a WUSCHEL-related homeobox domain transcription factor, is a key regulator of crown root growth and development in rice (Oryza sativa. L). In addition to specifically activating crown root development, WOX11 is also involved in lateral root initiation, root hair formation, and abiotic stresses. However, the gene regulatory network downstream of WOX11 remains largely unknown. Here, we studied the transcriptome of wox11 root tips by RNA-Seq and determined direct WOX11-binding targets by bioinformatic and biochemical analysis. The transcriptomic analysis revealed 664 differentially expressed genes, which covered a wide range of functions related to root development, cytokinin homeostasis/signaling, stress response, and redox metabolic processes. Bioinformatic analysis also revealed that the WOX11-binding motif was distributed over 41% (273/664) of the differentially expressed genes, and was mostly enriched in the promoter and intron regions. We used qRT-PCR and/or in situ hybridization to confirm co-expression of some of the WOX11-regulated genes in crown root development. We also used electrophoretic mobility shift assay and chromatin immunoprecipitation with anti-WOX11 antibody to validate direct regulation of these genes by WOX11. The analysis identified several genes that acted downstream of WOX11 in controlling crown root formation, cytokinin signaling, stress response, and redox metabolism. This work built a hierarchical regulatory model of WOX11 in rice crown root development.
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