Evidence map›Paper›PMID 28829969›Full record

ArticleCurrent biology : CB2017

Cell Polarity: Spot-On Cdc42 Polarization Achieved on Demand.

Andrew B Goryachev, Marcin Leda

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew B GoryachevThe University of Edinburgh, School of Biological Sciences, Institute of Cell Biology, Centre for Synthetic and Systems Biology, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address: Andrew.Goryachev@ed.ac.uk.
Marcin LedaThe University of Edinburgh, School of Biological Sciences, Institute of Cell Biology, Centre for Synthetic and Systems Biology, Max Born Crescent, Edinburgh EH9 3BF, UK.
Wellcome Centre for Cell Biology · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G001855/1
6 · The paper itself

Abstract

A new study deploys optogenetics to induce the yeast bud on demand, at a site determined by a laser spot. The authors definitively prove that the initiation of cell polarization is driven by the Bem1-mediated positive feedback loop and reveal novel features of its regulation by the cell cycle.

Indexed as

cdc42 GTP-Binding Protein, Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdaptor Proteins, Signal TransducingCell CycleCell PolaritySaccharomyces cerevisiaeAdaptor Proteins, Signal TransducingBEM1 protein, S cerevisiaecdc42 GTP-Binding Protein, Saccharomyces cerevisiaeSaccharomyces cerevisiae Proteins

Identifiers

PMID28829969
OpenAlexW2746491986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.