Evidence map›Paper›PMID 28829790›Full record

ArticlePloS one2017

Disparities in Kaposi sarcoma incidence and survival in the United States: 2000-2013.

Kathryn E Royse, Firas El Chaer, E Susan Amirian, Christine Hartman, Susan E Krown, Thomas S Uldrick, Jeannette Y Lee, Zachary Shepard, Elizabeth Y Chiao

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 67 citations in OpenAlex.

  1. Clinical Predictors and Incidence of Kaposi Sarcoma Among Males With HIV in the Treat-All Era in the United States and Canada.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
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  20. Kaposi Sarcoma Rates Among Persons Living With Human Immunodeficiency Virus in the United States: 2008-2016.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Kathryn E RoyseCenter of Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, United States of America.
Firas El ChaerDepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas, United States of America.
E Susan AmirianDan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, United States of America.
Christine HartmanCenter of Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, United States of America.
Susan E KrownAIDS Malignancy Consortium, New York, New York, United States of America.
Thomas S UldrickHIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Jeannette Y LeeDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Zachary ShepardDepartment of Undergraduate Education, Baylor College of Medicine, Houston, Texas, United States of America.
Elizabeth Y ChiaoCenter of Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, United States of America.ORCID http://orcid.org/0000-0001-5752-2916
Michael E. DeBakey VA Medical Center · USBaylor College of Medicine · USNational Institutes of Health · USThe University of Texas MD Anderson Cancer Center · USUniversity of Arkansas for Medical Sciences · US

Funding

University of Southern CaliforniaU01CA121947 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MITSUYASU, RONALD T. · 2006 to 2014
$54.7M
(PQ3) Identifying Novel Pharmacologic Risk factors for Common Non-AIDS Defining Cancers in Individuals with Well-controlled HIV InfectionR01CA206476 · NCI · BAYLOR COLLEGE OF MEDICINE · PI KRAMER, JENNIFER R · 2016 to 2019
$3.0M
NCI NIH HHS R01 CA206476NCI NIH HHS U01 CA121947
6 · The paper itself

Abstract

objectiveGeographic and racial disparities may contribute to variation in the incidence and outcomes of HIV-associated cancers in the United States.

methodUsing the Surveillance, Epidemiology, and End Results (SEER) database, we analyzed Kaposi sarcoma (KS) incidence and survival by race and geographic region during the combined antiretroviral therapy era. Reported cases of KS in men from 2000 to 2013 were obtained from 17 SEER cancer registries. Overall and age-standardized KS incidence rates were calculated and stratified by race and geographic region. We evaluated incidence trends using joinpoint analyses and calculated adjusted hazard ratios (aHR) for overall and KS-specific mortality using multivariable Cox proportional hazards models.

resultsOf 4,455 KS cases identified in men younger than 55 years (median age 40 years), the annual percent change (APC) for KS incidence significantly decreased for white men between 2001 and 2013 (APC -4.52, p = 0.02). The APC for AA men demonstrated a non-significant decrease from 2000-2013 (APC -1.84, p = 0.09). Among AA men in the South, however, APC has significantly increased between 2000 and 2013 (+3.0, p = 0.03). In addition, compared with white men diagnosed with KS during the same time period, AA men were also more likely to die from all causes and KS cancer-specific causes (aHR 1.52, 95% CI 1.34-1.72, aHR 1.49, 95% CI 1.30-1.72 respectively).

conclusionAlthough overall KS incidence has decreased in the U.S., geographic and racial disparities in KS incidence and survival exist.

Indexed as

AdultHumansIncidenceMaleMiddle AgedSarcoma, KaposiSurvival AnalysisUnited StatesYoung Adult

Identifiers

PMID28829790
PMCPMC5567503
OpenAlexW2747659490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.