Evidence map›Paper›PMID 28829786›Full record

ArticlePloS one2017

Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects.

Marzia Scarpari, Massimo Reverberi, Alessia Parroni, Valeria Scala, Corrado Fanelli, Chiara Pietricola, Slaven Zjalic, Vittoria Maresca, Agostino Tafuri, Maria R Ricciardi and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Food science & nutrition · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Antibacterial Activity of Essential Oils andAntibiotics (Basel, Switzerland) · 2020
    Article
  9. Review
  10. Article
  11. Use of the Secreted Proteome ofInternational journal of molecular sciences · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Marzia ScarpariSapienza University, Dept. of Environmental Biology, P.le Aldo Moro 5, Roma, Italy.
Massimo ReverberiSapienza University, Dept. of Environmental Biology, P.le Aldo Moro 5, Roma, Italy.ORCID http://orcid.org/0000-0003-3671-6783
Alessia ParroniSapienza University, Dept. of Environmental Biology, P.le Aldo Moro 5, Roma, Italy.
Valeria ScalaResearch Unit for Plant Pathology, Council for Agricultural Research and Economics, Rome, Italy, Roma, Italy.
Corrado FanelliSapienza University, Dept. of Environmental Biology, P.le Aldo Moro 5, Roma, Italy.
Chiara PietricolaSapienza University, Dept. of Environmental Biology, P.le Aldo Moro 5, Roma, Italy.
Slaven ZjalicDepartment of Ecology, Agronomy and Aquaculture, University of Zadar, HR, Zadar.
Vittoria MarescaIFO-S- Gallicano, Roma, Italy.
Agostino TafuriDepartment of Clinical and Molecular Medicine, Hematology, "Sant'Andrea" University Hospital Sapienza, University of Rome Roma.
Maria R RicciardiDepartment of Clinical and Molecular Medicine, Hematology, "Sant'Andrea" University Hospital Sapienza, University of Rome Roma.
Roberto LicchettaDepartment of Clinical and Molecular Medicine, Hematology, "Sant'Andrea" University Hospital Sapienza, University of Rome Roma.
Simone MirabiliiDepartment of Clinical and Molecular Medicine, Hematology, "Sant'Andrea" University Hospital Sapienza, University of Rome Roma.
Aris SveronisDept Life Sciences, Univ. Trieste, Trieste, Italy.
Paola CescuttiDept Life Sciences, Univ. Trieste, Trieste, Italy.
Roberto RizzoDept Life Sciences, Univ. Trieste, Trieste, Italy.
Sapienza University of Rome · ITLaboratory of Molecular Genetics · PLUniversity of Trieste · ITSan Gallicano Hospital · ITUniversity of Zadar · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mushrooms represent a formidable source of bioactive compounds. Some of these may be considered as biological response modifiers; these include compounds with a specific biological function: antibiotics (e.g. plectasin), immune system stimulator (e,g, lentinan), antitumor agents (e.g. krestin, PSK) and hypolipidemic agents (e.g. lovastatin) inter alia. In this study, we focused on the Chinese medicinal mushroom "yun zhi", Trametes versicolor, traditionally used for (cit.) "replenish essence and qi (vital energy)". Previous studies indicated the potential activity of extracts from culture filtrate of asexual mycelia of T. versicolor in controlling the growth and secondary metabolism (e.g. mycotoxins) of plant pathogenic fungi. The quest of active principles produced by T. versicolor, allowed us characterising an exo-polysaccharide released in its culture filtrate and naming it Tramesan. Herein we evaluate the biological activity of Tramesan in different organisms: plants, mammals and plant pathogenic fungi. We suggest that the bioactivity of Tramesan relies mostly on its ability to act as pro antioxidant molecule regardless the biological system on which it was applied.

Indexed as

Carbohydrate ConformationChromatography, GelMagnetic Resonance SpectroscopyPolysaccharidesSpectrometry, Mass, Electrospray IonizationTrametesPolysaccharides

Identifiers

PMID28829786
PMCPMC5567496
OpenAlexW2749480145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.