ReviewMetabolites2017
Extracellular Microbial Metabolomics: The State of the Art.
Review in Metabolites, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.
- Microbial Community Associations With Listeria monocytogenes in Food Processing Environments: A Systematic Review and Meta-Analysis.Comprehensive reviews in food science and food safety · 2025Pooled it
- A Randomized Double-Blind, Placebo-Controlled Study to Evaluate the Anti-Skin-Aging Effect of LactoSporin - The Extracellular Metabolite fromClinical, cosmetic and investigational dermatology · 2023Trial
- Metabolomics in Microbial Genetic Resource Conservation: From Strain Identity to Functional Preservation.Methods in molecular biology (Clifton, N.J.) · 2027Review
- High-throughput mass spectrometry for screening microbial culture supernatants for aromatic amino acids and selected derivatives.Biotechnology reports (Amsterdam, Netherlands) · 2026Article
- Hydrocinnamic Acid From Candida albicans: Isolation, Characterization, and Antibacterial Activity Against Multidrug-Resistant Bacteria.Biomedical chromatography : BMC · 2026Article
- Inorganic Carbon Modulates Emulsification Activity and Transcriptional Responses inMolecules (Basel, Switzerland) · 2026Article
- NMR Based Real-Time Analysis of Exometabolites Decodes the Mechanism of Action of Antibacterial Molecules, Nanoparticles, and Materials.Analytical chemistry · 2026Article
- Extracellular Metabolite Profiling in COMetabolites · 2026Article
- Linking antioxidant activity to strain-specific exometabolomic profiles in probioticCurrent research in food science · 2026Article
- GCMS-based evaluation, characterization and in silico analysis of antimicrobial metabolites in the crude extract of cold-adaptedAIMS microbiology · 2026Article
- Article
- Complex Kinetic Models Predict β-Carotene Production and Reveal Flux Limitations in RecombinantACS synthetic biology · 2025Article
- Sample Preparation for Single Cell Mass Spectrometry Metabolomics Studies: Combined Cell Washing, Quenching, Drying, and Storage.Journal of visualized experiments : JoVE · 2025Article
- Exploring the Modulation of Extracellular Metabolites in DifferentFood science of animal resources · 2025Article
- Microbial Metabolites: A Sustainable Approach to Combat Plant Pests.Metabolites · 2025Review
- A review on bacteria-derived antioxidant metabolites: their production, purification, characterization, potential applications, and limitations.Archives of pharmacal research · 2025Review
- Critical assessment of quenching and extraction/sample preparation methods for microorganisms in metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2025Review
- Microbial Fermentation in Food and Beverage Industries: Innovations, Challenges, and Opportunities.Foods (Basel, Switzerland) · 2025Review
- Metabolic reprogramming in PGPR reveals cross-feeding-driven physiological shifts and metabolic adaptations.Frontiers in microbiology · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microorganisms produce and secrete many primary and secondary metabolites to the surrounding environment during their growth. Therefore, extracellular metabolites provide important information about the changes in microbial metabolism due to different environmental cues. The determination of these metabolites is also comparatively easier than the extraction and analysis of intracellular metabolites as there is no need for cell rupture. Many analytical methods are already available and have been used for the analysis of extracellular metabolites from microorganisms over the last two decades. Here, we review the applications and benefits of extracellular metabolite analysis. We also discuss different sample preparation protocols available in the literature for both types (e.g., metabolites in solution and in gas) of extracellular microbial metabolites. Lastly, we evaluate the authenticity of using extracellular metabolomics data in the metabolic modelling of different industrially important microorganisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.