Evidence map›Paper›PMID 28829358›Full record

ArticleInternational journal of molecular sciences2017

Impact of Platelet-Rich Plasma on Viability and Proliferation in Wound Healing Processes after External Radiation.

Yvonne Reinders, Oliver Felthaus, Gero Brockhoff, Fabian Pohl, Norbert Ahrens, Lukas Prantl, Frank Haubner

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Platelet Rich Plasma in Gynecology-Discovering Undiscovered-Review.International journal of environmental research and public health · 2022
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yvonne ReindersDepartment of Otorhinolaryngology, Division of Facial Plastic Surgery, University Hospital Regensburg, 93053 Regensburg, Germany. yvonne.reinders@ukr.de.
Oliver FelthausDepartment of Plastic, Aesthetic, Hand & Reconstructive Surgery, University Hospital Regensburg, 93053 Regensburg, Germany. oliver.felthaus@ukr.de.
Gero BrockhoffDepartment of Gynaecology and Obstetrics, University Medical Centre Regensburg, 93053 Regensburg, Germany. gero.brockhoff@ukr.de.
Fabian PohlDepartment of Radiotherapy, University Hospital Regensburg, 93053 Regensburg, Germany. fabian.pohl@ukr.de.
Norbert AhrensDepartment of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, 93053 Regensburg, Germany. norbert.ahrens@ukr.de.
Lukas PrantlDepartment of Plastic, Aesthetic, Hand & Reconstructive Surgery, University Hospital Regensburg, 93053 Regensburg, Germany. lukas.prantl@ukr.de.
Frank HaubnerDepartment of Otorhinolaryngology, Division of Facial Plastic Surgery, University Hospital Regensburg, 93053 Regensburg, Germany. frank@fhaubner.de.
University Hospital Regensburg · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet-rich plasma is a current subject of studies on chronic wound healing therapy due to possible pro-angiogenic effects. Microvascular compromise represents the major component in radiogenic wound healing complications. The effects of platelet-rich plasma on irradiated cells of the cutaneous wound healing process are poorly understood so far. In this study, the interaction of endothelial cells and adipose-derived stem cells in conjunction with treatment with platelet-rich plasma is investigated in the context of radiation effects. Therefore, the expression of surface-marker CD90 and CD31 was determined. Moreover, cell proliferation and viability after external radiation was analyzed with and without treatment by platelet-rich plasma.

Indexed as

Platelet-Rich PlasmaWound HealingAdipose TissueBiomarkersCell ProliferationCells, CulturedCell SurvivalEndothelial CellsHumansImmunophenotypingRadiation InjuriesRadiotherapyBiomarkershuman adipose-derived stem cellsmicrovascular endothelial cellsplatelet-rich plasmaradiation therapy

Identifiers

PMID28829358
PMCPMC5578205
OpenAlexW2747861532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.