ArticlePublic health nutrition2017
Vitamin D insufficiency/deficiency is associated with insulin resistance in Brazilian children, regardless of body fat distribution.
Article in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Circulating levels of 25-hydroxyvitamin D in relation to hypertension in children and adolescents: a systematic review and dose-response meta-analysis of epidemiologic studies with GRADE assessment.Journal of translational medicine · 2025Pooled it
- Vitamin D status and blood pressure in children and adolescents: a systematic review of observational studies.Systematic reviews · 2021Pooled it
- Associations of economic vulnerability and food insecurity with the Planetary Health Diet in children: PASE study (Brazil).Frontiers in nutrition · 2025Article
- The excess body fat is a potential mediator between consumption of ultra-processed foods and cardiometabolic risk in normal-weight Brazilian children.Frontiers in nutrition · 2025Article
- Obesogenic neighborhood environment is associated with body fat and low-grade inflammation in Brazilian children: could the mother's BMI be a mediating factor?Public health nutrition · 2023Article
- Dietary inflammatory index scores are associated with atherogenic risk in Brazilian schoolchildren.Public health nutrition · 2021Article
- Pro- and anti-inflammatory adipokines are associated with cardiometabolic risk markers in Brazilian schoolchildren.European journal of pediatrics · 2021Article
- The dietary inflammatory index is associated with anti- and pro-inflammatory adipokines in Brazilian schoolchildren.European journal of nutrition · 2021Article
- TAG-glucose (TyG) index in childhood: an estimate of cut-off points and the relation to cardiometabolic risk in 4- to 9-year-old children.Public health nutrition · 2021Article
- Cutoff point estimation for serum vitamin D concentrations to predict cardiometabolic risk in Brazilian children.European journal of clinical nutrition · 2020Article
- Effect of Hypovitaminosis D on Lipid Profile in Hypothyroid Patients in Saudi Arabia.Oxidative medicine and cellular longevity · 2020Article
- Agreement of body adiposity index (BAI) and paediatric body adiposity index (BAIp) in determining body fat in Brazilian children and adolescents.Public health nutrition · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the prevalence of vitamin D insufficiency and deficiency and its association with cardiometabolic risk factors, controlled by adiposity, in a representative sample of prepubescent children.
designCross-sectional population-based study. Body composition was evaluated by dual-energy X-ray absorptiometry. Anthropometric measures and blood pressure were performed. Laboratory analyses were performed to determine the levels of vitamin D (25-hydroxyitamin D; 25(OH)D), glucose, insulin, serum lipids and intact parathyroid hormone. Dietary intake was assessed by three 24 h recalls.
settingViçosa, Minas Gerais, Brazil, 2015. SUBJECTS: Representative sample of 378 children aged 8 and 9 years from urban schools.
resultsInadequate serum concentrations of 25(OH)D were diagnosed in more than half of the children and none of them met the recommended vitamin D intake. After adjusting for confounding factors in the multiple regression analysis, lower prevalence of insulin resistance and hypertriacylglycerolaemia was found in children with serum 25(OH)D levels ≥75 nmol/l (prevalence ratio=0·25; 95 % CI 0·08, 0·85) and ≥50 nmol/l (prevalence ratio=0·61; 95 % CI 0·37, 0·99), respectively. However, after adjusting for different indicators of adiposity, insulin resistance remained independently associated and the association with hypertriacylglycerolaemia was lost after adjusting for central adiposity. The prevalence of vitamin D insufficiency/deficiency was associated with the number of cardiometabolic alterations in children.
conclusionsThe study results showed that prevalence of vitamin D insufficiency/deficiency was high among the children and insulin resistance was the main cardiometabolic alteration associated with this condition, even in a tropical climate country such as Brazil.
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