Evidence map›Paper›PMID 28829051›Full record

Trial reportNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018

Dopamine Transporter and Reward Anticipation in a Dimensional Perspective: A Multimodal Brain Imaging Study.

Manon Dubol, Christian Trichard, Claire Leroy, Anca-Larisa Sandu, Mehdi Rahim, Bernard Granger, Eleni T Tzavara, Laurent Karila, Jean-Luc Martinot, Eric Artiges

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
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  6. Review
  7. Article
  8. Article
  9. Article
  10. Syntaxin 1 SerScience advances · 2023
    Article
  11. Article
  12. The pharmacological treatment of schizophrenia: How far have we come?PCN reports : psychiatry and clinical neurosciences · 2022
    Review
  13. Review
  14. Article
  15. Article
  16. Anhedonia and Suicide.Current topics in behavioral neurosciences · 2022
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Manon DubolINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Christian TrichardINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Claire LeroyINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Anca-Larisa SanduINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.ORCID 0000-0002-5555-4129
Mehdi RahimParietal Project Team-INRIA, CEA, Neurospin, Gif-Sur-Yvette, France.
Bernard GrangerINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Eleni T TzavaraINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Laurent KarilaINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Jean-Luc MartinotINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Eric ArtigesINSERM, Research Unit 1000 'Neuroimaging and Psychiatry', Paris Sud University-Paris Saclay University, Paris Descartes University, Maison de Solenn, Paris & Service Hospitalier Frédéric Joliot, Orsay, France.
Université Paris-Sud · FRInstitut national de recherche en sciences et technologies du numérique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine function and reward processing are highly interrelated and involve common brain regions afferent to the nucleus accumbens, within the mesolimbic pathway. Although dopamine function and reward system neural activity are impaired in most psychiatric disorders, it is unknown whether alterations in the dopamine system underlie variations in reward processing across a continuum encompassing health and these disorders. We explored the relationship between dopamine function and neural activity during reward anticipation in 27 participants including healthy volunteers and psychiatric patients with schizophrenia, depression, or cocaine addiction, using functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) multimodal imaging with a voxel-based statistical approach. Dopamine transporter (DAT) availability was assessed with PET and [

Indexed as

RewardAdultAnticipation, PsychologicalBrainDopamine Plasma Membrane Transport ProteinsFemaleHumansMagnetic Resonance ImagingMaleMultimodal ImagingNerve NetPhotic StimulationPositron-Emission TomographyPsychomotor PerformanceDopamine Plasma Membrane Transport ProteinsSLC6A3 protein, human

Identifiers

PMID28829051
PMCPMC5809789
OpenAlexW2749422257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.