ArticleNeuroscience bulletin2017
Longitudinal Alterations of Local Spontaneous Brain Activity in Parkinson's Disease.
Article in Neuroscience bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Altered regional homogeneity in Parkinson's disease with mild cognitive impairment: a resting-state fMRI study.Frontiers in psychology · 2026Article
- Longitudinal Multimodal Functional Imaging: An Essential Tool for Visualizing Pathologic Progression in Parkinson's Disease.Journal of movement disorders · 2025Article
- Network localization of regional homogeneity alterations in Parkinson's disease.Frontiers in aging neuroscience · 2025Article
- Altered functional connectivity of the primary motor cortex in tremor dominant and postural instability gait difficulty subtypes of early drug-naive Parkinson's disease patients.Frontiers in neurology · 2023Article
- Article
- Altered Default Mode Network Functional Connectivity in Parkinson's Disease: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neuroscience · 2022Article
- Abnormal brain activities in multiple frequency bands in Parkinson's disease with apathy.Frontiers in neuroscience · 2022Article
- Longitudinal brain connectivity changes and clinical evolution in Parkinson's disease.Molecular psychiatry · 2021Article
- Stability of AI-Enabled Diagnosis of Parkinson's Disease: A Study Targeting Substantia Nigra in Quantitative Susceptibility Mapping Imaging.Frontiers in neuroscience · 2021Article
- Cell-Type-Specific Gene Modules Related to the Regional Homogeneity of Spontaneous Brain Activity and Their Associations With Common Brain Disorders.Frontiers in neuroscience · 2021Article
- Regional Neural Activity Changes in Parkinson's Disease-Associated Mild Cognitive Impairment and Cognitively Normal Patients.Neuropsychiatric disease and treatment · 2021Article
- The Relationship between Side of Onset and Cerebral Regional Homogeneity in Parkinson's Disease: A Resting-State fMRI Study.Parkinson's disease · 2020Article
- A Radiomics Approach to Predicting Parkinson's Disease by Incorporating Whole-Brain Functional Activity and Gray Matter Structure.Frontiers in neuroscience · 2020Article
- Levodopa Changes Functional Connectivity Patterns in Subregions of the Primary Motor Cortex in Patients With Parkinson's Disease.Frontiers in neuroscience · 2020Article
- ALFF and ReHo Mapping Reveals Different Functional Patterns in Early- and Late-Onset Parkinson's Disease.Frontiers in neuroscience · 2020Article
- Oscillation-specific nodal alterations in early to middle stages Parkinson's disease.Translational neurodegeneration · 2019Review
- Imaging of Motor Cortex Physiology in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2018Review
- Longitudinal Progression Markers of Parkinson's Disease: Current View on Structural Imaging.Current neurology and neuroscience reports · 2018Review
- Brain Atrophy and Reorganization of Structural Network in Parkinson's Disease With Hemiparkinsonism.Frontiers in human neuroscience · 2018Article
- Biomarker Discovery in Parkinson's Disease: Present Challenges and Future Opportunities.Neuroscience bulletin · 2017Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We used resting-state fMRI to evaluate longitudinal alterations in local spontaneous brain activity in Parkinson's disease (PD) over a 2-year period. Data were acquired from 23 PD patients at baseline and follow-up, and 27 age- and sex-matched normal controls. Regional homogeneity (ReHo) and voxel-based-morphometry (VBM) were used to identify differences in local spontaneous brain activity and grey matter volume. With disease progression, we observed a progressive decrease in ReHo in the sensorimotor cortex, default-mode network, and left cerebellum, but increased ReHo in the supplementary motor area, bilateral temporal gyrus, and hippocampus. Moreover, there was a significant positive correlation between the rates of ReHo change in the left cerebellum and the rates of change in the Unified Parkinson's Disease Rating Scale-III scores. VBM revealed no significant differences in the grey matter volume among the three sets of acquisitions. We conclude that ReHo may be a suitable non-invasive marker of progression in PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.