Evidence map›Paper›PMID 28828529›Full record

ReviewPediatric nephrology (Berlin, Germany)2018

Clinical management of nocturnal enuresis.

Eberhard Kuwertz-Bröking, Alexander von Gontard

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07126977 (The Effect of Video Game-Based Balance Exercises Added to Standard Rehabilitation on Clinical Symptoms and Pelvic Floor Muscle Functions in Children With Lower Urinary Tract Dysfunction), which is not on this map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07126977 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Video Game-Based Balance Exercises Added to Standard Rehabilitation on Clinical Symptoms and Pelvic Floor Muscle Functions in Children With Lower Urinary Tract Dysfunction

TypeinterventionalSponsorBahçeşehir UniversityRan2025 to 2026Enrolled30ConditionsLower Urinary Tract DysfunctionArmsUrotherapy training, Diaphragmatic Breathing Exercise, Biofeedback-Assisted Pelvic Floor Muscle Exercises, Video Game-Based Balance Exercise Training, Functional Exercise Training
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Copeptin in the diagnosis and management of renal tubular disorders.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. SunCloud: A mobile application for children with urinary incontinence.Journal of evaluation in clinical practice · 2025
    Article
  11. Article
  12. Article
  13. Approach to nocturnal enuresis in children.Singapore medical journal · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eberhard Kuwertz-BrökingPediatric Nephrology, University Children's Hospital Münster, Waldeyerstrasse 22, 48149, Muenster, Germany. kuwertz-broeking@t-online.de.ORCID 0000-0001-6399-0126
Alexander von GontardDepartment of Child and Adolescent Psychiatry, Saarland University Hospital, 66421, Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nocturnal enuresis (NE) is a common health problem. Approximately 10% of 7-year-old children wet the bed regularly during sleep. Enuresis can be categorized into monosymptomatic (MEN) and nonmonosymptomatic (NMEN) forms. MEN occurs without any other symptoms of bladder dysfunction. NMEN is associated with dysfunction of the lower urinary tract with or without daytime incontinence. The rate of comorbid gastrointestinal, behavioral, and emotional disorders is elevated depending upon the subtype of NE. A careful clinical history is fundamental to the evaluation of enuresis. Diagnostic procedures include medical history and psychological screening with questionnaires, bladder and bowel diary, physical examination, urinalysis, ultrasound, and examination of residual urine. The mainstay of treatment is urotherapy with information and psychoeducation about normal lower urinary tract function, the underlying cause of MEN, disturbed bladder dysfunction in the child with NMEN and instructions about therapeutic strategies. Alarm therapy and the use of desmopressin have been shown to be effective in randomized trials. Children with NMEN first need treatment of the underlying daytime functional bladder problem before treatment of nocturnal enuresis. In patients with findings of overactive bladder, besides urotherapy, anticholinergic drugs may be useful.

Indexed as

Patient Education as TopicAffective SymptomsBiofeedback, PsychologyChildCholinergic AntagonistsComorbidityDeamino Arginine VasopressinGastrointestinal DiseasesHumansNocturnal EnuresisProblem BehaviorPsychometricsRandomized Controlled Trials as TopicTreatment OutcomeUltrasonographyUrinalysisCholinergic AntagonistsDeamino Arginine VasopressinAlarm treatmentChildrenDesmopressinNocturnal enuresisUrotherapy

Identifiers

PMID28828529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.