ArticleProstate international2017
Fibrinogen and D-dimer levels in prostate cancer: Preliminary results.
Article in Prostate international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Neoadjuvant hormone therapy plus robot-assisted radical prostatectomy improves pathologic outcomes in high-risk prostate cancer: a retrospective cohort study.BMC urology · 2026Article
- Plasma fibrinogen levels towards cancer incidence: a systematic review and meta-analysis of epidemiological studies.Discover oncology · 2025Article
- To explore the risk factors of lymphovascular invasion in patients with upper tract urothelial carcinoma and construct a prediction model.Frontiers in oncology · 2025Article
- Peripheral Coagulation Parameters and Prostate Cancer Association: A Retrospective Study and Mendelian Randomization.Clinical Medicine Insights. Oncology · 2024Article
- The clinical association between coagulation indexes, platelet-related parameters, and bone metastasis of newly diagnosed prostate cancer.European journal of medical research · 2023Article
- Coagulation markers as independent predictors of prostate cancer aggressiveness: a retrospective cohort study.Scientific reports · 2023Article
- Paired Analysis of D-Dimer and Its Correlated Hemostatic Parameters in 30 Dogs with Neoplasms after Tumorectomy.Animals : an open access journal from MDPI · 2023Article
- Prognostic Value of C-Reactive Protein and Albumin in Neurocritically Ill Patients with Acute Stroke.Journal of clinical medicine · 2022Article
- A Novel Combination of Serum Markers in a Multivariate Model to Help Triage Patients Into "Low-" and "High-Risk" Categories for Prostate Cancer.Frontiers in oncology · 2022Article
- D-Dimer: A Potential Solution to Problems of Cancer Screening, Surveillance, and Prognosis Assessment.Cureus · 2021Review
- Preoperative risk stratification using plasma fibrinogen levels can predict lymphovascular invasion and poor prognosis in patients with upper urinary tract urothelial carcinoma.Molecular and clinical oncology · 2021Article
- Systemic Coagulation Markers Especially Fibrinogen Are Closely Associated with the Aggressiveness of Prostate Cancer in Patients Who Underwent Transrectal Ultrasound-Guided Prostate Biopsy.Disease markers · 2021Article
- Prognostic value of plasma fibrinogen and D-dimer levels in patients with surgically resected non-small cell lung cancer.Surgery today · 2020Article
- Is Preoperative Fibrinogen Associated with the Survival Prognosis of Gastric Cancer Patients? A Multi-centered, Propensity Score-Matched Retrospective Study.World journal of surgery · 2020Article
- D-Dimer Combined with Fibrinogen Predicts the Risk of Venous Thrombosis in Fracture Patients.Emergency medicine international · 2020Article
- Prognostic Value of the Preoperative Plasma D-Dimer Levels in Patients with Upper Tract Urothelial Carcinoma in a Retrospective Cohort Study.OncoTargets and therapy · 2020Article
- Clinical association between pre-treatment levels of plasma fibrinogen and bone metastatic burden in newly diagnosed prostate cancer patients.Chinese medical journal · 2019Article
- The positive immunostaining of TMPRSS2-ERG is not associated with unfavourable outcomes and biochemical recurrence after radical prostatectomy in Turkish patients.Central European journal of urology · 2018Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProstate cancer is one of the most common malignancy in men. The main risk factors for coagulation activation and thrombosis are malignancy and older age. The thrombosis risk may be associated with increased level of coagulation markers such as fibrinogen and D-dimer. The aim of this study is evaluate the relationship between coagulation markers and prostate cancer.
methodsThis prospective study includes the patients who underwent transrectal ultrasound guided prostate biopsy and prostate surgery was performed between January 2015 and January 2016. Plasma prostate specific antigen (PSA), free PSA (fPSA), percentage fPSA, D-dimer and fibrinogen levels were measured before the procedures. The patients were divided into two groups according to the pathology results. The patients with benign prostate hyperplasia were in group 1 and the patients with prostate cancer were in group 2.
resultsThere were 76 patients in the current study. There were 53 patients in group 1 and 23 patients in group 2. The mean age of the patients, PSA, fPSA, fibrinogen and D-dimer levels was 65.33 ± 7.47 years, 8.21 ± 4.59, 1.41 ± 0.74 ng/ml, 309.75 ± 80.46 mg/dl, 0.42 ± 0.39 ug/ml in group 1. In group 2; the mean age of the patients, PSA, fPSA, fibrinogen and D-dimer levels was 66.08 ± 6.7 years, 145.69 ± 509.35, 7.32 ± 15 ng/ml, 312.16 ± 69.48 mg/dl, 1.09 ± 2.11 ug/ml. The prostate biopsy and transurethral surgery were performed in 64(%84.21) and 12(%15.79) patients.
conclusionThe present study demonstrated that plasma D-dimer level was higher in patients with prostate cancer. Further studies that include large number of patients are needed to define the relationship between prostate cancer and coagulation disorder.
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