Evidence map›Paper›PMID 28828226›Full record

Observational studyBrain and behavior2017

Serum galectin-3 levels and delirium among postpartum intensive care unit women.

Ying Zhu, Wei Hu, Ming-Li Zhu, Ting Yin, Jun Su, Jian-Rong Wang

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Observational
  5. Review
  6. Prediction of Delirium in the Critically Ill Obstetric Patients: An Old Friend to the Rescue?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  7. Correlation of C-reactive Protein with Delirium in Obstetrics Intensive Care Unit: A Tertiary Center Experience.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ying ZhuDepartment of Intensive Care Unit The Hangzhou First People's Hospital Nanjing Medical University Hangzhou China.
Wei HuDepartment of Intensive Care Unit The Hangzhou First People's Hospital Nanjing Medical University Hangzhou China.ORCID 0000-0002-3691-7545
Ming-Li ZhuDepartment of Intensive Care Unit The Hangzhou First People's Hospital Nanjing Medical University Hangzhou China.
Ting YinDepartment of Intensive Care Unit The Hangzhou First People's Hospital Nanjing Medical University Hangzhou China.
Jun SuDepartment of Intensive Care Unit The Hangzhou First People's Hospital Nanjing Medical University Hangzhou China.
Jian-Rong WangDepartment of Intensive Care Unit The Hangzhou First People's Hospital Nanjing Medical University Hangzhou China.
Hangzhou First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInflammation correlates with delirium. Galectin-3 is a proinflammatory protein. This study aimed to determine relation of serum galectin-3 levels to delirium of postpartum intensive care unit (ICU) women. MATERIALS AND

methodsIn this prospective observational study, serum galectin-3, S100B, and C-reactive protein levels of 412 postpartum ICU women and 412 healthy women were measured. Delirium and Acute Physiology and Chronic Health Care Evaluation II (APCHCE II) scores were recorded.

resultsSerum levels of galectin-3, S100B, and C-reactive protein were significantly elevated in the postpartum women than in the healthy women. Galectin-3 levels were highly associated with APCHCE II scores and S100B and C-reactive protein levels. Galectin-3, C-reactive protein, and S100B levels and APCHCE II scores were identified as independent predictors for delirium. Area under the curve (AUC) of serum galectin-3 levels was similar to that of S100B levels, and significantly exceeded those of C-reactive protein levels and APCHCE II scores. Moreover, galectin-3 significantly improved the AUCs of APCHCE II scores, S100B levels, and C-reactive protein levels.

conclusionsGalectin-3, involved in inflammatory process underlying delirium-related brain injury, might be a potential biomarker to predict delirium of postpartum ICU women.

Indexed as

Critical IllnessAdultBiomarkersChinaC-Reactive ProteinDeliriumFemaleGalectin 3HumansImmunoassayInflammationIntensive Care UnitsMiddle AgedProspective StudiesPuerperal DisordersYoung AdultBiomarkersC-Reactive ProteinGalectin 3deliriumgalectin‐3intensive care unitpostpartumwomen

Identifiers

PMID28828226
PMCPMC5561326
OpenAlexW2737617129

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.