Evidence map›Paper›PMID 28828051›Full record

ArticleMaedica2016

Telocytes - a Hope for Cardiac Repair after Myocardial Infarction.

Ruxandra Dragoi Galrinho, Catalin Gabriel Manole, Dragos Vinereanu

Abstract read
In one paragraph

Article in Maedica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ruxandra Dragoi Galrinho"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; University and Emergency Hospital, Bucharest, Romania ; "Victor Babes" National Institute of Research Development in the Pathology Domain and Biomedical Sciences, Bucharest, Romania.
Catalin Gabriel Manole"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; "Victor Babes" National Institute of Research Development in the Pathology Domain and Biomedical Sciences, Bucharest, Romania.
Dragos Vinereanu"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; University and Emergency Hospital, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases, particularly myocardial infarction, remain the leading cause of morbidity and mortality worldwide, even though pharmacological and interventional therapies improved significantly in the last years. Moreover, despite encouraging results of cell - based therapies in experimental myocardial infarction models, clinical trials showed inconsistent and modest efficiency. Therefore the next step should be the revealing of a new cell type, capable of regenerating the damaged myocardium. Telocytes (TCs), a relatively new type of interstitial cells, were described few years ago and are credited with important roles in regenerative therapies. In this paper we review their most important characteristics and functions, showing the evidences of their potential role in cardiac repair and regeneration. Our research leads to the conclusion that TCs might be a novel target for therapeutic strategies in myocardial infarction.

Identifiers

PMID28828051
PMCPMC5543526

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.