Evidence map›Paper›PMID 28827930›Full record

ArticleIndian journal of palliative care

Fluoroscopy-guided Neurolytic Splanchnic Nerve Block for Intractable Pain from Upper Abdominal Malignancies in Patients with Distorted Celiac Axis Anatomy: An Effective Alternative to Celiac Plexus Neurolysis - A Retrospective Study.

Arif Ahmed, Divesh Arora

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Indian journal of palliative care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06978673 (Comparison of Neurolytic Block Techniques for the Treatment of Abdominal Visceral Pain and Their Influence On The Quality of Life of Patients With Cancer), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06978673 nanot yet recruitingnot on this map

Comparison of Neurolytic Block Techniques for the Treatment of Abdominal Visceral Pain and Their Influence On The Quality of Life of Patients With Cancer

TypeinterventionalSponsorInstituto do Cancer do Estado de São PauloRan2025 to 2026Enrolled64ConditionsCancer, Malignant Tumors, Abdominal Cancer, Cancer Pain, Visceral PainArmsSplanchnic nerve neurolysis - 5 ml of absolute alcohol (100%), Celiac Plexus Neurolysis - 5 ml of absolute alcohol (100%)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Percutaneous splanchnic nerve neurolysis analgesic efficacy and safety for cancer-related pain: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. 16. Pain in chronic pancreatitis.Pain practice : the official journal of World Institute of Pain · 2025
    Review
  5. Splanchnic neurolysis for severe cancer pain caused by abdominal paraaortic lymph node metastasis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Pain management in chronic pancreatitis.World journal of clinical cases · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. The value of angio-CT system on splanchnic nerve neurolysis.Diagnostic and interventional radiology (Ankara, Turkey) · 2021
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Arif AhmedDepartment of Anesthesiology and Pain Medicine, Asian Institute of Medical Sciences, Faridabad, India.
Divesh AroraDepartment of Anesthesiology and Pain Medicine, Asian Institute of Medical Sciences, Faridabad, India.
Asian Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe pain from upper gastrointestinal malignancy leads to considerable morbidity. The celiac plexus and splanchnic nerve neurolysis are good therapeutic options. Although splanchnic nerve neurolysis less frequently performed, but it has an edge over celiac plexus as it can be performed in patients with altered celiac plexus anatomy by enlarged lymph nodes.

methodsThe fluoroscopy-guided splanchnic nerve neurolysis was done in about 21 patients with intractable upper abdominal pain with pain intensity of ≥7 in numerical rating scale (NRS) from upper gastrointestinal cancers with distorted celiac plexus anatomy from enlarged celiac lymph nodes as seen by computed tomography scan after positive diagnostic splanchnic nerve neurolysis. The demographic features, pain intensity, daily opioid dose, functional status and quality of life was measured at baseline and 1 week, 1 and 3 months after the procedure.

resultsThere was a significant improvement in pain intensity, opioid requirement, functional status, and physical components quality of life after the neurolysis (

conclusionThe fluoroscopy-guided splanchnic nerve neurolysis results significant pain relief, decrease in opioid intake, improvement in functional status, and quality of life for up to 3 months in upper abdominal pain from gastrointestinal cancers in patients with distorted celiac lymph node anatomy not amenable to celiac plexus neurolysis.

Indexed as

Celiac plexusfluoroscopysplanchnic nerve neurolysisupper gastrointestinal cancer pain

Identifiers

PMID28827930
PMCPMC5545952
OpenAlexW2736233354

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.