Evidence map›Paper›PMID 28827898›Full record

ArticleMediators of inflammation2017

IL-10 and socs3 Are Predictive Biomarkers of Dengue Hemorrhagic Fever.

Lilian Karem Flores-Mendoza, Tania Estrada-Jiménez, Virginia Sedeño-Monge, Margarita Moreno, María Del Consuelo Manjarrez, Guadalupe González-Ochoa, Lourdes Millán-Pérez Peña, Julio Reyes-Leyva

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Viruses · 2022
    Review
  17. Review
  18. Low Activation of CD8Journal of immunology research · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Lilian Karem Flores-MendozaCentro de Investigación Biomédica de Oriente, HGZ5, Instituto Mexicano del Seguro Social, Km 4.5 Carretera Atlixco-Metepec, 74360 Metepec, PUE, Mexico.ORCID 0000-0002-6490-1364
Tania Estrada-JiménezCentro de Investigación Biomédica de Oriente, HGZ5, Instituto Mexicano del Seguro Social, Km 4.5 Carretera Atlixco-Metepec, 74360 Metepec, PUE, Mexico.
Virginia Sedeño-MongeDepartamento de Ciencias de la Salud, Universidad Popular Autónoma del Estado de Puebla, 21 Sur 1103, 72410 Puebla, PUE, Mexico.
Margarita MorenoHospital General de Zona No. 5, Instituto Mexicano del Seguro Social, Km 4.5 Carretera Atlixco-Metepec, 74360 Metepec, PUE, Mexico.
María Del Consuelo ManjarrezHospital General de Zona No. 5, Instituto Mexicano del Seguro Social, Km 4.5 Carretera Atlixco-Metepec, 74360 Metepec, PUE, Mexico.
Guadalupe González-OchoaDepartamento de Ciencias Químico Biológicas y Agropecuarias, División de Ciencias e Ingeniería, Universidad de Sonora, 85880 Navojoa, SON, Mexico.
Lourdes Millán-Pérez PeñaLaboratorio de Bioquímica y Biología Molecular, Centro de Química, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla, Edif. 103 F, CU-BUAP, San Manuel, 72570 Puebla, PUE, Mexico.
Julio Reyes-LeyvaCentro de Investigación Biomédica de Oriente, HGZ5, Instituto Mexicano del Seguro Social, Km 4.5 Carretera Atlixco-Metepec, 74360 Metepec, PUE, Mexico.ORCID 0000-0001-9415-6011
Mexican Social Security Institute · MXUniversidad Popular Autónoma del Estado de Puebla · MXBenemérita Universidad Autónoma de Puebla · MXUniversidad de Sonora · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCytokines play important roles in the physiopathology of dengue infection; therefore, the suppressors of cytokine signaling (

objectiveTo explore the association of cytokine and

methodsBlood samples of 48 patients with confirmed dengue infection were analyzed. Amounts of interleukins IL-2, IL-4, IL-6, and IL-10, interferon- (IFN-)

resultsIncreased levels of IL-10 and socs3 and lower expression of

conclusionSimultaneous changes in IL-10 and

Indexed as

AnimalsBiomarkersFemaleFlow CytometryHumansInterferon-gammaInterleukin-10Interleukin-2Interleukin-4Interleukin-6MaleSevere DengueSuppressor of Cytokine Signaling 1 ProteinSuppressor of Cytokine Signaling 3 ProteinTumor Necrosis Factor-alphaBiomarkersInterferon-gammaInterleukin-10Interleukin-2Interleukin-4Interleukin-6Suppressor of Cytokine Signaling 1 ProteinSuppressor of Cytokine Signaling 3 ProteinTumor Necrosis Factor-alpha

Identifiers

PMID28827898
PMCPMC5554562
OpenAlexW2739789031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.