ArticleScientific reports2017
Cognitive fatigue in individuals with traumatic brain injury is associated with caudate activation.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Using functional connectivity changes associated with cognitive fatigue to delineate a fatigue network.Scientific reports · 2020Trial
- Testing the ego-depletion effect in optimized conditions.PloS one · 2019Trial
- Towards a domain-general mechanistic model of fatigue: application to Functional Neurological Disorder.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Autologous adipose-derived mesenchymal stromal cells for chronic traumatic brain injury.Brain : a journal of neurology · 2026Article
- Brain fatigue in Graves' disease: symptoms and presentation of a possible mechanism at the cellular level.European thyroid journal · 2026Review
- The critical role of the basal ganglia in post-stroke fatigue: A pilot study.Neuroimage. Reports · 2026Article
- The differential effect of chronological age and brain age on cognitive fatigue: new metrics, new insights.Journal of neurology · 2026Article
- The brain fatigue syndrome: a cross-diagnostic phenomenon.Frontiers in human neuroscience · 2026Article
- Brain functional connectivity after Stroop task induced cognitive fatigue.Scientific reports · 2025Article
- The Brain Fatigue Syndrome-Symptoms, Probable Definition, and Pathophysiological Mechanisms.Journal of clinical medicine · 2025Review
- Neuroimaging markers of cognitive fatigue in individuals with post-acute sequelae of SARS-CoV-2 infection.Brain and cognition · 2025Article
- Exploring the n-back task: insights, applications, and future directions.Frontiers in human neuroscience · 2025Review
- Assessing prefrontal cortex activity in Graves' disease: a functional near-infrared spectroscopy study.Frontiers in human neuroscience · 2025Article
- Fatigue in Multiple Sclerosis: A Resting-State EEG Microstate Study.Brain topography · 2024Article
- Probing sustained attention and fatigue across the lifespan.PloS one · 2024Article
- Decoding visual fatigue in a visual search task selectively manipulated via myopia-correcting lenses.Frontiers in neuroscience · 2024Article
- Brain spatial reconciliation through multisensory integration in the impact of pandemic fatigue on workplace.Frontiers in human neuroscience · 2024Article
- Evaluating the effects of brain injury, disease and tasks on cognitive fatigue.Scientific reports · 2023Article
- The relationship between mental fatigue, depression, and cognition in Graves' disease.European thyroid journal · 2023Article
- Clinician reports of self-awareness after traumatic brain injury: a retrospective chart review.BMC health services research · 2022Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated differences in brain activation associated with cognitive fatigue between persons with traumatic brain injury (TBI) and healthy controls (HCs). Twenty-two participants with moderate-severe TBI and 20 HCs performed four blocks of a difficult working memory task and four blocks of a control task during fMRI imaging. Cognitive fatigue, assessed before and after each block, was used as a covariate to assess fatigue-related brain activation. The TBI group reported more fatigue than the HCs, though their performance was comparable. Regarding brain activation, the TBI group showed a Task X Fatigue interaction in the caudate tail resulting from a positive correlation between fatigue and brain activation for the difficult task and a negative relationship for the control task. The HC group showed the same Task X Fatigue interaction in the caudate head. Because we had prior hypotheses about the caudate, we performed a confirmatory analysis of a separate dataset in which the same subjects performed a processing speed task. A relationship between Fatigue and brain activation was evident in the caudate for this task as well. These results underscore the importance of the caudate nucleus in relation to cognitive fatigue.
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