ArticleAmerican journal of botany2017
Comparative transcriptomics indicate changes in cell wall organization and stress response in seedlings during spaceflight.
Article in American journal of botany, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 74 citations in OpenAlex.
- Cross-species transcriptomics uncovers shared responses to water deficiency in plants.The plant genome · 2026Article
- Suborbital spaceflight reveals rapid changes in gene expression accompanying the transition to and from space.NPJ microgravity · 2026Article
- Multiomics analysis of the molecular and single-cell responses of rice after deep-space flight on Chang'e-5.Nature communications · 2026Article
- Potential regulatory modules to integrate microgravity signals into flowering pathways in Arabidopsis thaliana grown in space.NPJ microgravity · 2025Article
- Rotifers in space: transcriptomic response of the bdelloid rotifer Adineta vaga aboard the International Space Station.BMC biology · 2025Article
- Translational insights into abiotic interactions: From Arabidopsis to crop plants.The Plant cell · 2025Review
- Exploring plant responses to altered gravity for advancing space agriculture.Plant communications · 2025Review
- The Growth of Soybean (Cells · 2025Article
- Alterations in physiological and biochemical characteristics of Prunus sibirica seedlings raised from spaceflight seeds.PloS one · 2025Article
- Light has a principal role in the Arabidopsis transcriptomic response to the spaceflight environment.NPJ microgravity · 2024Article
- Using single-sample networks and genetic algorithms to identify radiation-responsive genes in rice affected by heavy ions of the galactic cosmic radiation with different LET values.Frontiers in plant science · 2024Article
- Microgravity and evasion of plant innate immunity by human bacterial pathogens.NPJ microgravity · 2023Review
- Glycome profiling and immunohistochemistry uncover changes in cell walls of Arabidopsis thaliana roots during spaceflight.NPJ microgravity · 2023Article
- Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome.NPJ microgravity · 2023Article
- Article
- Conserved plant transcriptional responses to microgravity from two consecutive spaceflight experiments.Frontiers in plant science · 2023Article
- Advancing the automation of plant nucleic acid extraction for rapid diagnosis of plant diseases in space.Frontiers in plant science · 2023Article
- Integrative transcriptomics and proteomics profiling ofFrontiers in plant science · 2023Article
- Genome-Wide Comparison of Structural Variations and Transposon Alterations in Soybean Cultivars Induced by Spaceflight.International journal of molecular sciences · 2022Article
- Red Light Enhances Plant Adaptation to Spaceflight and MarsLife (Basel, Switzerland) · 2022Review
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
premise of the studyPlants will play an important role in the future of space exploration as part of bioregenerative life support. Thus, it is important to understand the effects of microgravity and spaceflight on gene expression in plant development.
methodsWe analyzed the transcriptome of Arabidopsis thaliana using the Biological Research in Canisters (BRIC) hardware during Space Shuttle mission STS-131. The bioinformatics methods used included RMA (robust multi-array average), MAS5 (Microarray Suite 5.0), and PLIER (probe logarithmic intensity error estimation). Glycome profiling was used to analyze cell wall composition in the samples. In addition, our results were compared to those of two other groups using the same hardware on the same mission (BRIC-16). KEY
resultsIn our BRIC-16 experiments, we noted expression changes in genes involved in hypoxia and heat shock responses, DNA repair, and cell wall structure between spaceflight samples compared to the ground controls. In addition, glycome profiling supported our expression analyses in that there was a difference in cell wall components between ground control and spaceflight-grown plants. Comparing our studies to those of the other BRIC-16 experiments demonstrated that, even with the same hardware and similar biological materials, differences in results in gene expression were found among these spaceflight experiments.
conclusionsA common theme from our BRIC-16 space experiments and those of the other two groups was the downregulation of water stress response genes in spaceflight. In addition, all three studies found differential regulation of genes associated with cell wall remodeling and stress responses between spaceflight-grown and ground control plants.
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