ArticleProceedings of the National Academy of Sciences of the United States of America2017
Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Identification of novel reproducible combinatorial genetic risk factors for myalgic encephalomyelitis in the DecodeME patient cohort and commonalities with long COVID.Journal of translational medicine · 2026Article
- Positive selection on rare variants of IGF1R and BRD4 underlying the cold adaptation of wild boar.Genetics, selection, evolution : GSE · 2025Article
- Promoting health and survival through lowered body temperature.Nature aging · 2025Review
- Article
- Effects of Calorie Restriction on Preserving Male Fertility Particularly in a State of Obesity.Current obesity reports · 2024Review
- Healthy Aging in Times of Extreme Temperatures: Biomedical Approaches.Aging and disease · 2024Review
- Effect of different masses, ages, and coats on the thermoregulation of dogs before and after exercise across different seasons.Veterinary research communications · 2023Article
- Alterations in intestinal microbiota composition coincide with impaired intestinal morphology and dysfunctional ileal immune response in growing-finishing pigs under constant chronic heat stress.Journal of animal science and biotechnology · 2022Article
- IGF1R is a mediator of sex-specific metabolism in mice: Effects of age and high-fat diet.Frontiers in endocrinology · 2022Article
- Sexual dimorphic impact of adult-onset somatopause on life span and age-induced osteoarthritis.Aging cell · 2021Article
- IGF1R as a Potential Pharmacological Target in Allergic Asthma.Biomedicines · 2021Article
- Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.EMBO reports · 2021Article
- Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes.Biochimica et biophysica acta. Molecular basis of disease · 2021Review
- The feeding microstructure of male and female mice.PloS one · 2021Article
- Metabolic adaptation to calorie restriction.Science signaling · 2020Article
- Costs of exploratory behavior: the energy trade-off hypothesis and the allocation model tested under caloric restriction.Scientific reports · 2020Article
- IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer's Disease Transgenic Mouse Model.Frontiers in cellular neuroscience · 2020Article
- Activation of Kappa Opioid Receptor Regulates the Hypothermic Response to Calorie Restriction and Limits Body Weight Loss.Current biology : CB · 2019Article
- Gonadal hormones influence core body temperature during calorie restriction.Temperature (Austin, Tex.) · 2019Article
- Feeding-State-Dependent Modulation of Temperature Preference Requires Insulin Signaling in Drosophila Warm-Sensing Neurons.Current biology : CB · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 4 countries.
Funding
Abstract
When food resources are scarce, endothermic animals can lower core body temperature (T
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.