ArticleProceedings of the National Academy of Sciences of the United States of America2017
Evidence for cue-independent spatial representation in the human auditory cortex during active listening.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- An Augmented Reality Audio-Motor Training Game for Improving Speech-in-Noise Perception: Single-Arm Pilot Feasibility Study.JMIR formative research · 2026Article
- Neuronal Representation of Auditory Distance Percepts vs. Cues in Human Auditory Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Behavioral engagement facilitates auditory neuron responses beyond their receptive fields.PLoS biology · 2026Article
- The Effect of Modulation Enhancement Scheme on Speech Recognition in Spatial Noise Among Young Adults with Normal Hearing.Audiology research · 2026Article
- Joint Population Coding and Temporal Coherence Link an Attended Talker's Voice and Location Features in Naturalistic Multi-talker Scenes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Dual Representation of the Auditory Space.Brain sciences · 2024Review
- Preliminary Evidence for Global Properties in Human Listeners During Natural Auditory Scene Perception.Open mind : discoveries in cognitive science · 2024Article
- Cortical representation of musical pitch in event-related potentials.Biomedical engineering letters · 2023Article
- Human cortical processing of interaural coherence.iScience · 2022Article
- Large group differences in binaural sensitivity are represented in preattentive responses from auditory cortex.Journal of neurophysiology · 2022Article
- Cerebral Representation of Sound Localization Using Functional Near-Infrared Spectroscopy.Frontiers in neuroscience · 2021Article
- Binaural spatial adaptation as a mechanism for asymmetric trading of interaural time and level differences.The Journal of the Acoustical Society of America · 2020Article
- Cortical auditory distance representation based on direct-to-reverberant energy ratio.NeuroImage · 2020Article
- What Can Computational Models Learn From Human Selective Attention? A Review From an Audiovisual Unimodal and Crossmodal Perspective.Frontiers in integrative neuroscience · 2020Review
- Impoverished auditory cues limit engagement of brain networks controlling spatial selective attention.NeuroImage · 2019Article
- Cortical mechanisms of spatial hearing.Nature reviews. Neuroscience · 2019Review
- Electrophysiological responses to lateral shifts are not consistent with opponent-channel processing of interaural level differences.Journal of neurophysiology · 2019Article
- Neurons in primary auditory cortex represent sound source location in a cue-invariant manner.Nature communications · 2019Article
- Representation of Auditory Motion Directions and Sound Source Locations in the Human Planum Temporale.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Active Sound Localization Sharpens Spatial Tuning in Human Primary Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Few auditory functions are as important or as universal as the capacity for auditory spatial awareness (e.g., sound localization). That ability relies on sensitivity to acoustical cues-particularly interaural time and level differences (ITD and ILD)-that correlate with sound-source locations. Under nonspatial listening conditions, cortical sensitivity to ITD and ILD takes the form of broad contralaterally dominated response functions. It is unknown, however, whether that sensitivity reflects representations of the specific physical cues or a higher-order representation of auditory space (i.e., integrated cue processing), nor is it known whether responses to spatial cues are modulated by active spatial listening. To investigate, sensitivity to parametrically varied ITD or ILD cues was measured using fMRI during spatial and nonspatial listening tasks. Task type varied across blocks where targets were presented in one of three dimensions: auditory location, pitch, or visual brightness. Task effects were localized primarily to lateral posterior superior temporal gyrus (pSTG) and modulated binaural-cue response functions differently in the two hemispheres. Active spatial listening (location tasks) enhanced both contralateral and ipsilateral responses in the right hemisphere but maintained or enhanced contralateral dominance in the left hemisphere. Two observations suggest integrated processing of ITD and ILD. First, overlapping regions in medial pSTG exhibited significant sensitivity to both cues. Second, successful classification of multivoxel patterns was observed for both cue types and-critically-for cross-cue classification. Together, these results suggest a higher-order representation of auditory space in the human auditory cortex that at least partly integrates the specific underlying cues.
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