Evidence map›Paper›PMID 28827343›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Involvement of posttranscriptional regulation of

Yasuhiro Umemura, Nobuya Koike, Munehiro Ohashi, Yoshiki Tsuchiya, Qing Jun Meng, Yoichi Minami, Masayuki Hara, Moe Hisatomi, Kazuhiro Yagita

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 79 citations in OpenAlex.

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  8. Circadian clock-gated cell renewal controls time-dependent changes in taste sensitivity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  13. "Time Is out of Joint" in Pluripotent Stem Cells: How and Why.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yasuhiro UmemuraDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Nobuya KoikeDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Munehiro OhashiDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Yoshiki TsuchiyaDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Qing Jun MengFaculty of Biology, Medicine and Health, Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester M13 9PL, United Kingdom.
Yoichi MinamiDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Masayuki HaraDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Moe HisatomiDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Kazuhiro YagitaDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan; kyagita@koto.kpu-m.ac.jp.
Kyoto Prefectural University of Medicine · JPWellcome Centre for Cell-Matrix Research · GB

Funding

Medical Research Council G0900414
6 · The paper itself

Abstract

Circadian clock oscillation emerges in mouse embryo in the later developmental stages. Although circadian clock development is closely correlated with cellular differentiation, the mechanisms of its emergence during mammalian development are not well understood. Here, we demonstrate an essential role of the posttranscriptional regulation of

Indexed as

AnimalsCell DifferentiationCircadian ClocksCircadian RhythmCLOCK ProteinsGene Expression RegulationMiceMouse Embryonic Stem CellsPeriod Circadian ProteinsProtein Processing, Post-TranslationalRNA-Binding ProteinsRNA, MessengerCLOCK ProteinsPeriod Circadian ProteinsRNA-Binding ProteinsRNA, Messengercellular differentiationcircadian clockCLOCKontogenyposttranscriptional regulation

Identifiers

PMID28827343
PMCPMC5594651
OpenAlexW2745431530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.