Evidence map›Paper›PMID 28827262›Full record

ArticleBMJ open2017

Polymorphisms of the stem cell marker gene

Qing-Feng Liu, Zhi-Fei Zhang, Guang-Jie Hou, Guang-Yu Yang, Yi He

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. SNP rs2240688 inTranslational cancer research · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qing-Feng LiuDepartment of Thoracic Surgery, Henan Provincial People's Hospital (Zhengzhou University People's Hospital), Zhengzhou, China.
Zhi-Fei ZhangDepartment of Thoracic Surgery, Henan Provincial People's Hospital (Zhengzhou University People's Hospital), Zhengzhou, China.
Guang-Jie HouDepartment of Thoracic Surgery, Henan Provincial People's Hospital (Zhengzhou University People's Hospital), Zhengzhou, China.
Guang-Yu YangDepartment of Thoracic Surgery, Henan Provincial People's Hospital (Zhengzhou University People's Hospital), Zhengzhou, China.
Yi HeDepartment of Thoracic Surgery, Henan Provincial People's Hospital (Zhengzhou University People's Hospital), Zhengzhou, China.
Zhengzhou University · CNHenan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the prognostic relevance of four functional single nucleotide polymorphisms (SNPs) in

designRetrospective cohort study.

settingDepartment of General Surgery, in a general hospital, Henan Province, China.

participantsNSCLC patients aged ≥18 years, who were not receiving preoperative neoadjuvant therapies and had a blood sample available for genotyping, were eligible for inclusion. Those participants who were pregnant or breastfeeding, had a previous history of cancer, had other primary tumours, or who had had primary tumours of the skin and nasopharynx, were excluded from the study. OUTCOME MEASURES: The primary endpoint was OS, which was calculated from the date of enrolment until the date of death or date of last follow-up.

resultsThere was a total of 1383 participants, with a median age of 63 years; 726 (52.5%) were male. Compared with the

conclusionsThe study confirmed the significant association between the SNP

Indexed as

AC133 AntigenAdultAgedAged, 80 and overBiomarkers, TumorCarcinoma, Non-Small-Cell LungCase-Control StudiesChinaFemaleGenotypeHumansKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedPolymorphism, Single NucleotideAC133 AntigenBiomarkers, TumorPROM1 protein, humanCD133 polymorphismChinaNon-small cell lung canceroverall survival

Identifiers

PMID28827262
PMCPMC5724226
OpenAlexW2749179594

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.