Evidence map›Paper›PMID 28827219›Full record

ArticleCirculation2017

Death Receptor Signaling in the Heart: Cell Survival, Apoptosis, and Necroptosis.

Dulguun Amgalan, Yun Chen, Richard N Kitsis

Abstract readEditorialComment
In one paragraph

Article in Circulation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. TRAIL and its receptors in cardiac diseases.Frontiers in physiology · 2023
    Review
  6. Mitochondrial quality control in health and cardiovascular diseases.Frontiers in cell and developmental biology · 2023
    Review
  7. Review
  8. Does Pyroptosis Play a Role in Inflammasome-Related Disorders?International journal of molecular sciences · 2022
    Review
  9. Review
  10. COVID-lateral damage: cardiovascular manifestations of SARS-CoV-2 infection.Translational research : the journal of laboratory and clinical medicine · 2022
    Review
  11. Article
  12. Dexmedetomidine alleviates HMolecular biology reports · 2020
    Article
  13. Article
  14. Review
  15. Review
  16. Inflammation in myocardial injury: mesenchymal stem cells as potential immunomodulators.American journal of physiology. Heart and circulatory physiology · 2019
    Review
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Dulguun AmgalanFrom Departments of Medicine (Cardiology) and Cell Biology, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY.
Yun ChenFrom Departments of Medicine (Cardiology) and Cell Biology, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY.
Richard N KitsisFrom Departments of Medicine (Cardiology) and Cell Biology, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY. richard.kitsis@einstein.yu.edu.

Funding

Chaperone-Mediated Autophagy in Normal Cardiac Biology and Heart FailureR01HL138475 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KITSIS, RICHARD N · 2017 to 2020
$2.4M
A new molecular pathway for diabetic cardiomyopathyR01HL130861 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KITSIS, RICHARD N, YOSHIOKA, JUN · 2016 to 2019
$2.4M
Linking cell death and mitochondrial quality control mechanisms in heart diseaseR01HL128071 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DORN, GERALD W., KITSIS, RICHARD N · 2015 to 2018
$2.1M
NHLBI NIH HHS R01 HL128071NHLBI NIH HHS R01 HL130861NHLBI NIH HHS R01 HL138475
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell SurvivalNecrosisApoptosisHumansReceptors, Death DomainTNF Receptor-Associated Factor 2Receptors, Death DomainTNF Receptor-Associated Factor 2apoptosiscell deathEditorialsnecroptosisnecrosisTNFTRAF2

Identifiers

PMID28827219
PMCPMC5657500

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.