ArticleeLife2017
Tissue-specific regulation of BMP signaling by
Open access · goldAbstract read
In one paragraph
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 70 citations in OpenAlex.
- Impacts of N-glycanase1 (NGLY1) Down Regulation on the Function of Mitochondria.Journal of cellular biochemistry · 2026Article
- TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER triage checkpoint for BMP4/Dpp.Cell reports · 2026Article
- Tissue-specific I-Smad mechanisms revealed by structure-function analysis inLife science alliance · 2026Article
- TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER Triage Checkpoint for BMP4/Dpp.bioRxiv : the preprint server for biology · 2025Article
- NGLY1 deficiency - clinical features and therapeutic strategy.Journal of human genetics · 2025Review
- Impaired Proteostasis is Linked to Neurological Pathology in a Zebrafish NGLY1 Deficiency Model.Journal of inherited metabolic disease · 2025Article
- Article
- Systemic gene therapy corrects the neurological phenotype in a mouse model of NGLY1 deficiency.JCI insight · 2024Article
- Development of new NGLY1 assay systems - toward developing an early screening method for NGLY1 deficiency.Glycobiology · 2024Review
- Functional prediction of the potential NGLY1 mutations associated with rare disease CDG.Heliyon · 2024Article
- Development of a fluorescence and quencher-based FRET assay for detection of endogenous peptide:N-glycanase/NGLY1 activity.The Journal of biological chemistry · 2024Article
- NGLY1 mutations cause protein aggregation in human neurons.Cell reports · 2023Article
- Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila.Nature communications · 2023Article
- The genetic basis of wing spots in Pieris canidia butterflies.BMC genomics · 2023Article
- BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration.Developmental cell · 2022Article
- Comprehensive Analysis of the Structure and Function of Peptide:N-Glycanase 1 and Relationship with Congenital Disorder of Deglycosylation.Nutrients · 2022Review
- NGLY1 Deficiency, a Congenital Disorder of Deglycosylation: From Disease Gene Function to Pathophysiology.Cells · 2022Review
- Deficiency of N-glycanase 1 perturbs neurogenesis and cerebral development modeled by human organoids.Cell death & disease · 2022Article
- A method for assaying peptide: N-glycanase/N-glycanase 1 activities in crude extracts using an N-glycosylated cyclopeptide.Glycobiology · 2022Article
- Cytosolic O-GlcNAcylation and PNG1 maintain Drosophila gut homeostasis by regulating proliferation and apoptosis.PLoS genetics · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Antonio GaleoneDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-0201-3089
Seung Yeop HanDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Chengcheng HuangGlycometabolome Team, RIKEN Global Research Cluster, Saitama, Japan.
Akira HosomiGlycometabolome Team, RIKEN Global Research Cluster, Saitama, Japan.
Tadashi SuzukiGlycometabolome Team, RIKEN Global Research Cluster, Saitama, Japan.
Hamed Jafar-NejadDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID 0000-0001-6403-3379
Baylor College of Medicine · US
Funding
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5MSteps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, SAMACO, RODNEY C · 2014 to 2019
$7.8MFine-Tuning the Notch Signaling Pathway via O-GlucosylationR01GM084135 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JAFAR-NEJAD, HAMED · 2008 to 2017
$2.6MNegative regulation of Jagged1 by glycosylation: towards a mechanism-based therapy for Alagille syndromeR01DK109982 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI JAFAR-NEJAD, HAMED · 2016 to 2019
$1.6MNICHD NIH HHS U54 HD083092NIDDK NIH HHS R01 DK109982NIGMS NIH HHS R01 GM084135NIH HHS P40 OD018537
Abstract
Mutations in the human
Indexed as
AnimalsBone Morphogenetic ProteinsDrosophilaDrosophila ProteinsGastrointestinal TractGene Expression RegulationPeptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine AmidaseProtein Serine-Threonine KinasesReceptors, Cell SurfaceSignal TransductionBone Morphogenetic Proteinsdpp protein, DrosophilaDrosophila ProteinsPeptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine AmidaseProtein Serine-Threonine KinasesReceptors, Cell Surfacetkv protein, DrosophilaBMP signalingdevelopmental biologyD. melanogasterDrosophilamidgutNGLY1stem cells
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.