Evidence map›Paper›PMID 28826476›Full record

ArticleeLife2017

Eyeless uncouples mushroom body neuroblast proliferation from dietary amino acids in

Conor W Sipe, Sarah E Siegrist

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
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  8. Article
  9. Review
  10. Neural Stem Cell Reactivation in Cultured Drosophila Brain Explants.Journal of visualized experiments : JoVE · 2022
    Article
  11. Article
  12. A fly's eye view of quiescent neural stem cells.Oxford open neuroscience · 2022
    Review
  13. Glia-derived temporal signals orchestrate neurogenesis in theProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Nucleolar stress inBiology open · 2020
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Conor W SipeDepartment of Biology, University of Virginia, Charlottesville, United States.ORCID http://orcid.org/0000-0002-4455-6612
Sarah E SiegristDepartment of Biology, University of Virginia, Charlottesville, United States.ORCID http://orcid.org/0000-0003-0685-5387
University of Virginia · US

Funding

Cell growth and proliferation control in neural stem cellsR01GM120421 · NIGMS · UNIVERSITY OF VIRGINIA · PI SIEGRIST, SARAH ELIZABETH · 2016 to 2020
$1.6M
Developmental regulation of neural stem cell eliminationR00HD067293 · NICHD · UNIVERSITY OF VIRGINIA · PI SIEGRIST, SARAH ELIZABETH · 2013 to 2015
$706k
Nutrient-regulated stem cell proliferationF32NS096919 · NINDS · UNIVERSITY OF VIRGINIA · PI SIPE, CONOR · 2017 to 2019
$190k
NICHD NIH HHS R00 HD067293NIGMS NIH HHS R01 GM120421NINDS NIH HHS F32 NS096919
6 · The paper itself

Abstract

Cell proliferation is coupled with nutrient availability. If nutrients become limited, proliferation ceases, because growth factor and/or PI3-kinase activity levels become attenuated. Here, we report an exception to this generality within a subpopulation of

Indexed as

Amino AcidsAnimalsBrainCell CycleCell ProliferationDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsEatingGene Expression Regulation, DevelopmentalMemoryMushroom BodiesNeural Stem CellsNeurogenesisNeuronsPhosphatidylinositol 3-KinasesAmino AcidsDNA-Binding ProteinsDrosophila Proteinsey protein, DrosophilaPhosphatidylinositol 3-Kinasesdevelopmental biologydietD. melanogastereyelessneural stem cellneuroblastPax-6PI3-kinasestem cells

Identifiers

PMID28826476
PMCPMC5576483
OpenAlexW2742478263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.