Evidence map›Paper›PMID 28826457›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2017

Prevalence and risk factors of restrictive spirometry in a cohort of Peruvian adults.

T Siddharthan, M Grigsby, C H Miele, A Bernabe-Ortiz, J J Miranda, R H Gilman, R A Wise, J C Porter, J R Hurst, W Checkley

Abstract read
In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Clinical Characteristics and Medical Utilization of Smokers with Preserved Ratio Impaired Spirometry.International journal of chronic obstructive pulmonary disease · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study.American journal of respiratory and critical care medicine · 2018
    Observational
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

T SiddharthanDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
M GrigsbyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, Program in Global Disease Epidemiology and Control, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
C H MieleDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
A Bernabe-OrtizCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
J J MirandaCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
R H GilmanProgram in Global Disease Epidemiology and Control, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
R A WiseDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
J C PorterUniversity College London (UCL) Respiratory, Division of Medicine, UCL, London, UK.
J R HurstUniversity College London (UCL) Respiratory, Division of Medicine, UCL, London, UK.
W CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, Program in Global Disease Epidemiology and Control, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.

Funding

Training in noncommunicable diseases epidemiological, data science and Implementation Science research to strengthen evidence-based interventions, policy and control in Uganda.D43TW011401 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI Charles Batte, William Checkley · 2019 to 2026
$1.8M
Acute Lung Injury: Application of Novel Approaches to Longitudinal Data AnalysisR00HL096955 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHECKLEY, WILLIAM · 2011 to 2013
$723k
Reduction of air pollution through an LPG Intervention trial to improve pulmonary healthF32ES028577 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI SIDDHARTHAN, TRISHUL · 2017 to 2017
$60k
FIC NIH HHS D43 TW011401NHLBI NIH HHS HHSN268200900033CNHLBI NIH HHS R00 HL096955NIEHS NIH HHS F32 ES028577
6 · The paper itself

Abstract

introductionFew studies have described the prevalence of and lung function decline among those with a restrictive spirometric pattern (RSP) in low- and middle-income countries.

methodsWe analyzed prospective data from 3055 adults recruited across four diverse settings in Peru over a 3-year period. Multivariable logistic regression was used to study the association between the presence of restriction and associated risk factors. Multivariable linear mixed models were used to determine lung function decline.

resultsAmong 3055 participants, the average age was 55.4 years (SD 12.4); 49% were male. Overall prevalence of RSP was 4.7%, ranging from 2.8% (Lima) to 6.9% (Tumbes). The odds of having RSP were higher among those who lived in a rural environment (OR 2.19, 95%CI 1.43-3.37), had a diagnosis of diabetes (OR 1.94, 95%CI 1.10-3.40) and among women (OR 2.09, 95%CI 1.41-3.09). When adjusting for baseline lung function, adults with RSP had accelerated decline in forced expiratory volume in 1 s (FEV1) compared with non-obstructed, non-restricted individuals. DISCUSSION: RSP is prevalent particularly among women and in individuals living in rural settings of Peru. When adjusted for baseline lung function, participants with RSP had accelerated rates of FEV1 decline. Our findings are consistent with the notion that RSP is an insidious inflammatory condition with deleterious effects of lung function decline.

Indexed as

SpirometryAdultAgedAltitudeBody Mass IndexC-Reactive ProteinFemaleFollow-Up StudiesForced Expiratory VolumeHumansLogistic ModelsLongitudinal StudiesLung Diseases, ObstructiveMaleMiddle AgedPeruC-Reactive Protein

Identifiers

PMID28826457
PMCPMC8558895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.