ReviewHuman vaccines & immunotherapeutics2017
Immunotherapy for cow's milk allergy.
Review in Human vaccines & immunotherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- Cow milk protein allergy mimics in infancy.World journal of clinical pediatrics · 2025Review
- Practical issues of oral immunotherapy for egg or milk allergy.Clinical and experimental pediatrics · 2024Article
- Review
- Current Practice in Pediatric Cow's Milk Protein Allergy-Immunological Features and Beyond.International journal of molecular sciences · 2023Review
- Article
- Modulating Oxidative Stress in B Cells Promotes Immunotherapy in Food Allergy.Oxidative medicine and cellular longevity · 2022Article
- A2 adenosine receptor contributes to the development of cow's milk protein allergy via regulating regulatory T cells.Iranian journal of basic medical sciences · 2021Article
- Successful treatment of a patient with adult food allergy and severe asthma using omalizumab.Asia Pacific allergy · 2021Article
- Pre- and Neonatal Imprinting on Immunological Homeostasis and Epithelial Barrier Integrity byFrontiers in immunology · 2020Article
- Review
- Broad perspectives of allergen specific immunotherapy.Human vaccines & immunotherapeutics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral immunotherapy (OIT) is used regularly for young children with cow's milk (CM) allergy and has been shown to be effective in several studies. However, adverse events occur frequently during OIT. Furthermore, there are only 5 randomized controlled trial studies of CM-OIT and these are low-powered single center trials. Therefore, evidence levels are also low and sometimes frequent and severe allergic events occur during the OIT. Furthermore, there are no standardized protocols in pediatric allergy guidelines from several countries and studies with long-term follow-up observations and clinical tolerance defined as sustained unresponsiveness are rare. Additionally, clinical tolerance by OIT is generally not well defined and obscure. Thus, several problems remain to be resolved, however we hope OIT in combination with omalizumab and less allergenic heated CM products will resolve these problems in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.